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在一个不使用碘盐的社区中对甲状腺疾病的研究。

The study of thyroid diseases in a community not using iodized salt.

作者信息

Teng Xiaochun, Hu Fengnan, Teng Weiping, Wang Haixue, Shong Shaoquan, Shan Zhongyan, Jin Ying, Guan Haixia, Yang Fan, Gao Tianshu, Wang Weibo, Shi Xiaoguang, Teng Di

机构信息

Endocrinology Department, The First Affiliated Hospital, China Medical University, Shenyang 110001, China.

出版信息

Zhonghua Yu Fang Yi Xue Za Zhi. 2002 May;36(3):176-9.

PMID:12410951
Abstract

OBJECTIVE

To investigate the prevalence of thyroid diseases in a community which did not use iodized salt.

METHODS

The survey was conducted in Panshan, Liaoning Province. 1 103 inhabitants aged 14 years or more attended the examinations, which included questionnaire, physical examination and serum analysis. Iodine in the urine and thyroid B ultrasound examination were also conducted.

RESULTS

The prevalence of overt hyperthyroidism and hypothyroidism was 16.3 per thousand and 2.7 per thousand, respectively. Subclinical hyperthyroidism and hypothyroidism were detected in 37.2 per thousand and 9.1 per thousand of the subjects, respectively. Serum autoantibodies to thyroid were detected in 10.9% of the entire population. The prevalence of goiter was 20.7% (diffuse goiter 16.8% and nodular goiter 3.9%).

CONCLUSION

In the iodine deficient areas, perhaps autoimmununization is not only related to the development of goiter but is also the main cause of subclinical hyperthyroidism and hypothyroidism.

摘要

目的

调查一个未使用碘盐的社区中甲状腺疾病的患病率。

方法

调查在辽宁省盘山进行。1103名14岁及以上居民参加了检查,包括问卷调查、体格检查和血清分析。同时进行了尿碘和甲状腺B超检查。

结果

显性甲状腺功能亢进和甲状腺功能减退的患病率分别为千分之16.3和千分之2.7。亚临床甲状腺功能亢进和甲状腺功能减退在受试者中的检出率分别为千分之37.2和千分之9.1。在整个人口中,甲状腺自身抗体的检出率为10.9%。甲状腺肿的患病率为20.7%(弥漫性甲状腺肿16.8%,结节性甲状腺肿3.9%)。

结论

在碘缺乏地区,自身免疫可能不仅与甲状腺肿的发生有关,也是亚临床甲状腺功能亢进和甲状腺功能减退的主要原因。

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