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[感染性全膝关节置换术的治疗]

[Treatment of infected total knee arthroplasty].

作者信息

Weng Xisheng, Li Lianhua, Qiu Guixing, Li Junwei, Tian Ye, Hen Jianxiong, Wang Yipeng, Jin Jin, Ye Qibin, Zhao Hong

机构信息

Department Of Orthopaedics, Peking Union Hospital, Peking Union Medical University, Beijing 100730, China.

出版信息

Zhonghua Wai Ke Za Zhi. 2002 Sep;40(9):669-72.

Abstract

OBJECTIVE

To investigate the treatment of infected total knee arthroplasty (TKA).

METHODS

Between 1983 and 2000, 6 patients with infection after TKAs were treated, including 2 men and 4 women, aged on average 63 years (44 - 75 years). Initial knee arthroplasty was performed for osteoarthritis in 4 patients and for rheumatoid arthritis in 2 knees. The timing of diagnosis of infection after knee arthroplasty averaged 50 months (range, 1 month-11 years). Simple debridement and antibiotic treatment were prescribed for 3 patients, debridement and one-stage reimplantation for 1, debridement and two-stage reimplantation for 1, and athrodesis for 1.

RESULTS

Of the 3 patients with simple debridement, one was cured, one failed but underwent athrodesis later, and one lost to follow up. Two patients with reimplantation were cured and had good function recovery. All of the 6 patients were followed up on average for 4 years. No infection recurred except one who lost to follow-up.

CONCLUSIONS

Management of infection after total knee arthroplasty includes antibiotic suppression and debridement with prosthesis retention, insertion of another prosthesis as a one-stage or two-stage exchange technique, knee arthrodesis and amputation. These treatments have specific indications. To treat infection after total knee arthroplasty, suitable method should be taken according to patient's condition. Arthrodesis is the best salvage operation, though it may handicap patients' daily life. Reimplantation of another prosthesis could maintain a functional joint.

摘要

目的

探讨感染性全膝关节置换术(TKA)的治疗方法。

方法

1983年至2000年间,对6例TKA术后感染患者进行了治疗,其中男性2例,女性4例,平均年龄63岁(44 - 75岁)。4例患者因骨关节炎行初次膝关节置换术,2例因类风湿关节炎行膝关节置换术。膝关节置换术后感染的诊断时间平均为50个月(范围为1个月至11年)。3例患者采用单纯清创及抗生素治疗,1例采用清创及一期再植入,1例采用清创及二期再植入,1例采用关节融合术。

结果

3例单纯清创患者中,1例治愈,1例失败但后来接受了关节融合术,1例失访。2例再植入患者治愈且功能恢复良好。6例患者均平均随访4年。除1例失访患者外,无感染复发。

结论

全膝关节置换术后感染的处理包括抗生素抑制及保留假体的清创、一期或二期置换技术再植入另一假体、膝关节融合术和截肢术。这些治疗方法有特定的适应证。治疗全膝关节置换术后感染,应根据患者情况采取合适的方法。关节融合术是最佳的挽救手术,尽管可能会给患者的日常生活带来不便。再植入另一假体可维持关节功能。

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