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[下丘脑后区在兔下丘脑-垂体-肾上腺系统反应实现中的功能作用]

[The functional role of the posterior hypothalamic field in realizing the responses of the hypothalamo-hypophyseal-adrenal system in rabbits].

作者信息

Shkhinek E K

出版信息

Probl Endokrinol (Mosk). 1975 Nov-Dec;21(6):59-65.

PMID:1241135
Abstract

The role played by the area of the posterior hypothalamic field in the realization of reactions of the hypophysis-adrenal system in rabbits in response to the stimuli of various nature was studied. Bilateral electrolytic damage of the area under study, without causing any significant changes in the concentration of 11-OCS of the plasma at rest, led to the statistically significant intensification of the hormonal shifts in response to the immobilization, administration of ethinizol and horse serum. Control injries in the preoptic area caused no changes of this kind, and in case of the horse serum led to reverse shifts. The data obtained permitted a conclusion to be drawn that, along with mosaicity of the neuronal structures of the hypothalamus responsible for the hypophysis-adrenal system function individual zones could possess some specific effects, this being expressed in macroinjuries.

摘要

研究了下丘脑后区在兔垂体 - 肾上腺系统对各种性质刺激的反应实现过程中所起的作用。对所研究区域进行双侧电解损伤,在静息状态下血浆11 - OCS浓度未引起任何显著变化,但在制动、给予乙氮唑和马血清后,激素变化在统计学上显著增强。视前区的对照损伤未引起此类变化,而在给予马血清的情况下则导致相反的变化。所获得的数据使我们可以得出结论,除了负责垂体 - 肾上腺系统功能的下丘脑神经元结构的镶嵌性外,个别区域可能具有一些特定作用,这在宏观损伤中表现出来。

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