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结核病发病率与卡介苗接种(作者译)

[Incidence of tuberculosis and BCG inoculation (author's transl)].

作者信息

Falk W, Lazarini W

出版信息

Wien Klin Wochenschr. 1975 Apr 18;87(8):266-70.

PMID:1241192
Abstract

The incidence of tuberculosis in childhood has declined throughout the world during the last decades. It is difficult to evaluate the role of BCG inoculation in achieving a decrease in incidence of the disease. The practice of administering BCG to children in general is thus a matter which is still under discussion and in which unanimity has not yet been achieved. However, it is generally agreed to recommend BCG inoculation in areas with a high incidence of active cases. This study was initiated in order to elicit the necessity of BCG inoculation in the city of Graz and, more widely, in the province of Styria (Austria). The incidence of active tuberculosis was investigated in children and adults over the past 12 years period. The incidence of active tuberculosis in children proved to be higher in rural areas than in Graz. The incidence of active tuberculosis in adults showed only a slight decrease during this 12-year period, the decrease being definitely more pronounced in Graz than in the rural areas. Considering the incidence rates of active tuberculosis it is advisable to continue BCG inoculation in infants and children, not only in the rural areas of Styria, but also in the city of Graz.

摘要

在过去几十年间,全球儿童结核病的发病率有所下降。难以评估卡介苗接种在降低该疾病发病率方面所起的作用。因此,普遍给儿童接种卡介苗这一做法仍是一个尚在讨论且未达成一致意见的问题。然而,人们普遍同意在活动性病例高发地区推荐接种卡介苗。开展这项研究是为了明确在格拉茨市乃至更广泛的奥地利施蒂里亚州进行卡介苗接种的必要性。对过去12年期间儿童和成人的活动性结核病发病率进行了调查。结果表明,农村地区儿童活动性结核病的发病率高于格拉茨市。在这12年期间,成人活动性结核病的发病率仅略有下降,格拉茨市的下降幅度明显大于农村地区。考虑到活动性结核病的发病率,不仅在施蒂里亚州的农村地区,而且在格拉茨市,继续对婴幼儿和儿童接种卡介苗是明智之举。

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