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入住重症监护病房的中风患者的治疗结果:来自一家澳大利亚教学医院的经验。

Outcome of stroke patients admitted to intensive care: experience from an Australian teaching hospital.

作者信息

Fanshawe M, Venkatesh B, Boots R J

机构信息

Department of Anaesthesia and Critical Care Medicine, Royal Brisbane Hospital, Queensland.

出版信息

Anaesth Intensive Care. 2002 Oct;30(5):628-32. doi: 10.1177/0310057X0203000515.

Abstract

The objective of this study was to determine the mortality rate and the functional outcomes of stroke patients admitted to the intensive care unit (ICU) and to identify predictors of poor outcome in this population. The records of all patients admitted to the ICU with the diagnosis of stroke between January 1994 and December 1999 were reviewed. Patients with subarachnoid haemorrhage were excluded. Data were collected on clinical and biological variables, risk factors for stroke and the presence of comorbidities. Mortality (ICU, in-hospital and three-month) and functional outcome were used as end-points. In the six-year-period, 61 patients were admitted to the ICU with either haemorrhagic or ischaemic stroke. Medical records were available for only 58 patients. There were 23 ischaemic and 35 haemorrhagic strokes. The ICU, in-hospital and three-month mortality rates were 36%, 47% and 52% respectively. There were no significant differences in the prevalence of premorbid risk factors between survivors and non-survivors. The mean Barthel score was significantly different between the independent and dependent survivors (94+/-6 vs 45+/-26, P<0.001). A substantial number of patients with good functional outcomes had lower Rankin scores (92% vs 11%, P<0.001). Only 46% of those who were alive at three months were functionally independent. Intensive care admission was associated with a high mortality rate and a high likelihood of dependent lifestyle after hospital discharge. Haemorrhagic stroke, fixed dilated pupil(s) and GCS <10 during assessment were associated with increased mortality and poor functional outcome.

摘要

本研究的目的是确定入住重症监护病房(ICU)的中风患者的死亡率和功能转归,并识别该人群预后不良的预测因素。回顾了1994年1月至1999年12月期间入住ICU且诊断为中风的所有患者的记录。蛛网膜下腔出血患者被排除。收集了临床和生物学变量、中风危险因素及合并症的数据。将死亡率(ICU、住院期间和三个月时)和功能转归作为终点指标。在这六年期间,61例出血性或缺血性中风患者入住了ICU。仅58例患者有病历记录。其中23例为缺血性中风,35例为出血性中风。ICU、住院期间和三个月时的死亡率分别为36%、47%和52%。幸存者和非幸存者病前危险因素的患病率无显著差异。独立幸存者和依赖幸存者的平均巴氏评分有显著差异(94±6 vs 45±26,P<0.001)。功能转归良好的患者中,有相当一部分Rankin评分较低(92% vs 11%,P<0.001)。三个月时存活的患者中,只有46%在功能上是独立的。入住重症监护病房与高死亡率及出院后依赖生活方式的高可能性相关。出血性中风、评估时固定散大瞳孔和格拉斯哥昏迷评分<10与死亡率增加和功能转归不良相关。

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