Jang Aeri, Bae Chang Hoon, Han Soo Jeong, Bae Hasuk
Department of Rehabilitation Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea.
Department of Rehabilitation Medicine, Ewha Womans University College of Medicine, Seoul, Korea.
Ann Rehabil Med. 2021 Feb;45(1):49-56. doi: 10.5535/arm.20111. Epub 2021 Feb 9.
To discuss the association between the length of stay at the intensive care unit (ICU) and sarcopenia among hemiplegic stroke patients.
This study evaluated 66 hemiplegic stroke patients with history of ICU admission using handgrip strength and bioelectrical impedance analysis to obtain height-adjusted appendicular skeletal muscle mass. The diagnosis of sarcopenia was made according to the muscle mass based on the Asian Working Group for Sarcopenia. The patients were divided into sarcopenic and non-sarcopenic groups. The two groups were statistically analyzed, and the significant factors with differences were studied. A multivariate logistic regression analysis was performed to examine the association between length of stay in the ICU and sarcopenia, after adjusting for potential confounders.
Among 66 hemiplegic patients with an ICU admission history, 12 patients were diagnosed with sarcopenia. Sarcopenia patients showed lower scores on the Korean version of the Modified Barthel Index and the Korean version of the Mini-Mental State Examination. Additionally, patients with sarcopenia had a longer length of stay in the ICU, and univariate and multivariate analyses confirmed that the ICU length of stay was significantly related to sarcopenia (adjusted odds ratio=1.187; 95% confidence interval, 1.019-1.382; p=0.028).
The length of stay in the ICU was significantly associated with sarcopenia in hemiplegic stroke patients.
探讨偏瘫性脑卒中患者在重症监护病房（ICU）的住院时长与肌肉减少症之间的关联。
本研究评估了66例有ICU住院史的偏瘫性脑卒中患者，通过握力和生物电阻抗分析来获取身高校正后的四肢骨骼肌质量。根据亚洲肌肉减少症工作组制定的基于肌肉质量的标准诊断肌肉减少症。将患者分为肌肉减少症组和非肌肉减少症组。对两组进行统计学分析，并研究存在差异的显著因素。在调整潜在混杂因素后，进行多因素逻辑回归分析以检验ICU住院时长与肌肉减少症之间的关联。
在66例有ICU住院史的偏瘫患者中，12例被诊断为肌肉减少症。肌肉减少症患者在韩国版改良巴氏指数和韩国版简易精神状态检查表上的得分较低。此外，肌肉减少症患者在ICU的住院时间更长，单因素和多因素分析均证实ICU住院时长与肌肉减少症显著相关（校正比值比=1.187；95%置信区间，1.019 - 1.382；p = 0.028）。
ICU住院时长与偏瘫性脑卒中患者的肌肉减少症显著相关。
