Morris Rhys J, Woodcock John P
Department of Medical Physics and Bioengineering, University of Wales College of Medicine, Cardiff, Wales.
Arch Surg. 2002 Nov;137(11):1269-73. doi: 10.1001/archsurg.137.11.1269.
Intermittent pneumatic compression will affect the arterial blood flow in the lower limb at moderate pressure, without requiring dependency.
Before-after trial.
Vascular ultrasound unit of a university hospital.
A volunteer sample of 19 healthy subjects without symptoms or history of vascular disease and 17 patients with peripheral arterial disease were studied. Six patients and 1 healthy volunteer were not included in the study group because of measurement difficulties or refusal when approached.
Common femoral artery blood flow velocities were measured with Doppler ultrasound during 10 minutes of intermittent compression of the calf and thigh at 60 mm Hg, while the subject was supine. The data were collected every 5 seconds from 4 minutes before to 4 minutes after the therapy period, and toe temperatures were also measured with an infrared radiometer.
Resting to postcompression percentage increases in flow velocity were measured, along with more representative measures of the total flow change during the intermittent compression period.
On compression, the blood flow velocity decreased slightly (15% in healthy subjects and 6% in patients) and increased on release (21% and 29%, respectively). Overall, blood flow did not decrease during therapy as expected (increases of 1% and 2%, respectively), and the toes of the patients warmed (by 2.2 degrees C).
This work confirms the initial hypothesis in both subject groups. There appears to be physiological justification for investigating intermittent compression as a therapy for patients with intermittent claudication and rest pain in the supine position as well as seated.
间歇性气动压迫在中等压力下会影响下肢动脉血流,且无需依赖体位。
前后对照试验。
一所大学医院的血管超声科。
对19名无血管疾病症状或病史的健康受试者及17名外周动脉疾病患者的志愿者样本进行了研究。6名患者和1名健康志愿者因测量困难或在研究人员联系时拒绝参与而未纳入研究组。
受试者仰卧时,在小腿和大腿以60毫米汞柱进行10分钟间歇性压迫期间,用多普勒超声测量股总动脉血流速度。在治疗期前4分钟至治疗期后4分钟,每5秒收集一次数据,并用红外辐射计测量趾温。
测量静息至压迫后血流速度的百分比增加,以及间歇性压迫期间总血流变化的更具代表性的指标。
压迫时,血流速度略有下降(健康受试者下降15%,患者下降6%),松开时血流速度增加(分别增加21%和29%)。总体而言,治疗期间血流并未如预期那样下降(分别增加1%和2%),患者的脚趾变暖(升高2.2摄氏度)。
这项研究在两个受试组中均证实了最初的假设。对于研究间歇性压迫作为仰卧位和坐位间歇性跛行及静息痛患者的一种治疗方法,似乎有生理学依据。