Guidetti Vincenzo, Galli Federica
Department of Child and Adolescent Neurology and Psychiatry, Interuniversity Center for the Study of Headache and Neurotransmitter Disorders Section of Rome, University of Rome La Sapienza, Via dei Sabelli 108, Italy.
Curr Pain Headache Rep. 2002 Dec;6(6):492-7. doi: 10.1007/s11916-002-0069-7.
Chronic daily headache is a challenge for clinical practitioners and researchers. Etiology, pathophysiology, diagnosis, treatment, and prognosis of chronic daily headache present many questions that need answers. A chance occurrence of psychiatric disorders (mostly anxiety and mood disorders) in patients with chronic daily headache should not be excluded. This results in the need to understand the involved mechanisms, which requires us to draw new insights into the etiology, diagnosis, treatment, and prognosis of chronic daily headache. Psychiatric comorbidity seems to be cross-related to each of these dimensions, although the meanings need to be drawn. Each domain is discussed, considering the status of knowledge and stressing the future lines of research.
慢性每日头痛对临床医生和研究人员来说是一项挑战。慢性每日头痛的病因、病理生理学、诊断、治疗及预后存在诸多需要解答的问题。慢性每日头痛患者偶然出现精神障碍（主要是焦虑和情绪障碍）的情况不应被排除。这就需要了解其中涉及的机制，而这要求我们对慢性每日头痛的病因、诊断、治疗及预后有新的认识。精神共病似乎与这些方面都存在交叉关联，尽管其具体含义仍有待明确。本文将对每个领域进行讨论，考量现有知识状况并着重强调未来的研究方向。
