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食管癌切除术后静脉补液与鼻空肠肠内营养的随机对照研究

Intravenous hydration versus naso-jejunal enteral feeding after esophagectomy: a randomised study.

作者信息

Page Richard D, Oo Aung Y, Russell Glen N, Pennefather Stephen H

机构信息

Department of Thoracic Surgery, The Cardiothoracic Centre, Thomas Drive, Liverpool L14 3PE, UK.

出版信息

Eur J Cardiothorac Surg. 2002 Nov;22(5):666-72. doi: 10.1016/s1010-7940(02)00489-x.

DOI:10.1016/s1010-7940(02)00489-x
PMID:12414028
Abstract

OBJECTIVE

Patients undergoing esophagectomy are typically nutritionally depleted and cannot establish oral feeding for up to a week after surgery. We have investigated the routine use of enteral feeding via a naso-jejunal tube.

METHODS

Forty consecutive patients undergoing a transthoracic esophagectomy for cancer were randomised to receive enteral feeding or intravenous crystalloid fluids after surgery. Nutritional indices were obtained prior to surgery and on the 7th post-operative day.

RESULTS

There were no post-operative deaths. Non-fatal complications occurred in 10 patients, without difference in morbidity between the two groups. Lean body mass did not change in either group over the study period. No differences in any other parameters were identified between the two groups.

CONCLUSION

Enteral feeding via a naso-jejunal tube is safe and well tolerated after esophagectomy. It is a simple method of providing nutritional support prior to the re-introduction of oral feeding. However it provides no measurable benefit over intravenous hydration only for patients undergoing routine esophagectomy.

摘要

目的

接受食管切除术的患者通常营养状况不佳,术后长达一周无法经口进食。我们研究了经鼻空肠管进行肠内营养的常规应用。

方法

连续40例因癌症接受经胸段食管切除术的患者被随机分为术后接受肠内营养或静脉输注晶体液两组。在手术前及术后第7天获取营养指标。

结果

无术后死亡病例。10例患者出现非致命性并发症,两组发病率无差异。在研究期间,两组的去脂体重均未改变。两组在任何其他参数上均未发现差异。

结论

食管切除术后经鼻空肠管进行肠内营养是安全的,耐受性良好。这是在重新经口进食前提供营养支持的一种简单方法。然而,对于接受常规食管切除术的患者,与仅静脉补液相比,它没有可测量的益处。

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