Tao Stanley, Meyer Dale R, Simon John W, Zobal-Ratner Jitka
Lions Eye Institute, Department of Ophthalmology, Albany Medical College, Albany, New York 12208, USA.
Ophthalmology. 2002 Nov;109(11):2108-11. doi: 10.1016/s0161-6420(02)01216-2.
To determine the efficacy of lacrimal balloon catheter dilatation in treating congenital nasolacrimal duct obstruction (CNLDO) as a primary procedure in children more than 18 months of age and in children who have failed lacrimal probing or silicone intubation.
Retrospective, interventional case series.
Fifty-nine patients, ranging in age from 15 months to 9 years (mean, 35.6 months), with 73 lacrimal systems diagnosed with CNLDO who underwent nasolacrimal balloon catheter dilatation. Thirty-four lacrimal systems (46.5%) had no previous procedures, whereas 39 lacrimal systems (53.5%) had failed probing, silicone intubation, or both.
Balloon catheter dilatation was performed following standard protocol, with a simplified regimen in most patients.
Clinical patency of the nasolacrimal duct after balloon dilatation was the main outcome measure and was defined as complete resolution of signs and symptoms (crusting, discharge, and increased tear meniscus). Age, inferior turbinate infracture, and Downe's syndrome as related to the main outcome measure were also analyzed.
Overall, 56 of the 73 lacrimal systems (76.7%) had complete resolution of symptoms. Twenty-seven of all 34 primary balloon catheter dilatations (79.4%) remained clinically patent, whereas 29 of all 39 secondary balloon catheter dilatations (74.4%) remained clinically patent after surgery (P = 0.8165). Thirty-nine of 47 lacrimal systems (82.9%) in children older than 24 months remained clinically patent, whereas 17 of 26 lacrimal systems (65.4%) in children younger than 24 months remained clinically patent (P = 0.1573). The mean age of patients with successful outcomes was 37 months, whereas the mean age of patients with failed balloon catheter dilatations was 32 months (P = 0.3924). In the secondary procedure group, analysis showed that the mean age of success (32 months) was greater than the mean age of failure (18 months; P = 0.0491). Within the secondary group, 16 of 17 lacrimal systems (94.1%) older than 24 months were successful, whereas 13 of 22 lacrimal systems (59.1%) younger than 24 months were successful (P = 0.0344).
Balloon catheter dilatation is an effective treatment for congenital nasolacrimal duct obstruction. In particular, balloon catheter dilatation in older children who failed previous probing is highly successful.
确定泪囊球囊导管扩张术治疗先天性鼻泪管阻塞(CNLDO)的疗效,该治疗作为18个月以上儿童以及泪道探通或硅胶管植入失败儿童的主要治疗方法。
回顾性干预病例系列研究。
59例患者,年龄范围为15个月至9岁(平均35.6个月),其73个泪道系统诊断为CNLDO并接受了鼻泪囊球囊导管扩张术。34个泪道系统(46.5%)既往未接受过治疗,而39个泪道系统(53.5%)泪道探通、硅胶管植入失败或两者均失败。
按照标准方案进行球囊导管扩张术,大多数患者采用简化方案。
球囊扩张术后鼻泪管的临床通畅情况是主要观察指标,定义为体征和症状(结痂、分泌物及泪液弯月面增加)完全消失。还分析了与主要观察指标相关的年龄、下鼻甲骨折及唐氏综合征情况。
总体而言,73个泪道系统中的56个(76.7%)症状完全消失。所有34例初次球囊导管扩张术中的27例(79.4%)术后临床通畅,而所有39例二次球囊导管扩张术中的29例(74.4%)术后临床通畅(P = 0.8165)。24个月以上儿童的47个泪道系统中的39个(82.9%)术后临床通畅,而24个月以下儿童的26个泪道系统中的17个(65.4%)术后临床通畅(P = 0.1573)。治疗成功患者的平均年龄为37个月,而球囊导管扩张术失败患者的平均年龄为32个月(P = 0.3924)。在二次治疗组中,分析显示成功患者的平均年龄(32个月)大于失败患者的平均年龄(18个月;P = 0.0491)。在二次治疗组中,24个月以上的17个泪道系统中的16个(94.1%)治疗成功,而24个月以下的22个泪道系统中的13个(59.1%)治疗成功(P = 0.0344)。
球囊导管扩张术是治疗先天性鼻泪管阻塞的有效方法。特别是,既往泪道探通失败的大龄儿童行球囊导管扩张术成功率很高。