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1
The Treatment of Congenital Nasolacrimal Duct Obstruction in Children: A Retrospective Review.儿童先天性鼻泪管阻塞的治疗:一项回顾性研究。
J Pediatr Ophthalmol Strabismus. 2018 Jan 1;55(1):65-67. doi: 10.3928/01913913-20170703-08. Epub 2017 Oct 9.
2
Probing for congenital nasolacrimal duct obstruction.探查先天性鼻泪管阻塞
Cochrane Database Syst Rev. 2017 Jul 12;7(7):CD011109. doi: 10.1002/14651858.CD011109.pub2.
3
[Comparing of Treatment Results of Monocanalicular and Bicanalicular Intubation in Inborn Lacrimal Duct Obstruction].[先天性泪道阻塞中单泪小管插管与双泪小管插管治疗结果的比较]
Cesk Slov Oftalmol. 2016 Fall;72(5):178-181.
4
Congenital Nasolacrimal Duct Obstruction: Comparison of Two Different Treatment Algorithms.先天性鼻泪管阻塞:两种不同治疗方案的比较
J Pediatr Ophthalmol Strabismus. 2016 Sep 1;53(5):285-91. doi: 10.3928/01913913-20160629-01. Epub 2016 Aug 4.
5
The natural process of congenital nasolacrimal duct obstruction and effect of lacrimal sac massage.先天性鼻泪管阻塞的自然病程及泪囊按摩的效果
Int Ophthalmol. 2016 Dec;36(6):845-849. doi: 10.1007/s10792-016-0208-5. Epub 2016 Mar 7.
6
[Comparison of balloon catheter dilatation and silicon intubation as the secondary treatment for congenital nasolacrimal duct obstruction after failed primary probing].[球囊导管扩张术与硅胶插管术作为先天性鼻泪管阻塞初次探通失败后的二级治疗方法的比较]
Zhonghua Yan Ke Za Zhi. 2016 Feb;52(2):123-8. doi: 10.3760/cma.j.issn.0412-4081.2016.02.009.
7
Comparison of treatment for congenital nasolacrimal duct obstruction: a systematic review and meta-analysis.先天性鼻泪管阻塞的治疗比较:一项系统评价和荟萃分析
Can J Ophthalmol. 2016 Feb;51(1):34-40. doi: 10.1016/j.jcjo.2015.10.002.
8
Success rate of late primary probing in congenital nasolacrimal duct obstruction.先天性鼻泪管阻塞延迟初次探查的成功率
J Pediatr Ophthalmol Strabismus. 2014 Nov-Dec;51(6):360-2. doi: 10.3928/01913913-20140909-02. Epub 2014 Sep 16.
9
Update on congenital nasolacrimal duct obstruction.先天性鼻泪管阻塞的最新进展。
Int Ophthalmol Clin. 2014 Summer;54(3):1-7. doi: 10.1097/IIO.0000000000000030.
10
Silicone intubation for nasolacrimal duct stenosis in adults: monocanalicular or bicanalicular intubation.成人鼻泪管狭窄的硅胶插管治疗:单泪小管或双泪小管插管
J Craniofac Surg. 2014 May;25(3):1009-11. doi: 10.1097/SCS.0000000000000708.

先天性鼻泪管阻塞(CNLDO):综述

Congenital Nasolacrimal Duct Obstruction (CNLDO): A Review.

作者信息

Vagge Aldo, Ferro Desideri Lorenzo, Nucci Paolo, Serafino Massimiliano, Giannaccare Giuseppe, Lembo Andrea, Traverso Carlo Enrico

机构信息

Eye Clinic of Genoa, Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health (DiNOGMI), University of Genova, 16132 Genova, Italy.

IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy.

出版信息

Diseases. 2018 Oct 22;6(4):96. doi: 10.3390/diseases6040096.

DOI:10.3390/diseases6040096
PMID:30360371
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6313586/
Abstract

Congenital nasolacrimal duct obstruction (CNLDO) is a common condition causing excessive tearing or mucoid discharge from the eyes, due to blockage of the nasolacrimal duct system. Nasolacrimal duct obstruction affects as many as 20% children aged <1 year worldwide and is often resolved without surgery. Available treatment options are conservative therapy, including observation, lacrimal sac massage and antibiotics, and invasive therapy. Observation, combined with conservative options, seems to be the best option in infants aged <1 year. Meanwhile, in children aged >1 year, nasolacrimal probing successfully addresses most obstructions. However, the most favorable timing for probing remains controversial. To alleviate persistent epiphora and mucous drainage that is refractory to probing, repeat probing, silicone tube intubation, balloon catheter dilation or dacryocystorhinostomy can be considered as available treatment options. Our review aims to provide an update to CNDO management protocols.

摘要

先天性鼻泪管阻塞(CNLDO)是一种常见病症,由于鼻泪管系统堵塞,导致眼睛出现过多流泪或黏液性分泌物。鼻泪管阻塞在全球范围内影响多达20%的1岁以下儿童,且通常无需手术即可缓解。现有的治疗选择包括保守治疗,如观察、泪囊按摩和使用抗生素,以及侵入性治疗。观察结合保守治疗方法,似乎是1岁以下婴儿的最佳选择。同时,对于1岁以上的儿童,鼻泪管探通术能成功解决大多数阻塞问题。然而,探通的最佳时机仍存在争议。为缓解探通治疗无效的持续性溢泪和黏液引流,可考虑重复探通、硅胶管插管、球囊导管扩张术或泪囊鼻腔吻合术等现有治疗方法。我们的综述旨在更新先天性鼻泪管阻塞的管理方案。