载脂蛋白E在单纯疱疹病毒1型经血行途径进入中枢神经系统中的作用。
Involvement of apolipoprotein E in the hematogenous route of herpes simplex virus type 1 to the central nervous system.
作者信息
Burgos Javier S, Ramirez Carlos, Sastre Isabel, Bullido María J, Valdivieso Fernando
机构信息
Departamento de Biología Molecular and Centro de Biología Molecular Severo Ochoa (C.S.I.C.-U.A.M.), Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain.
出版信息
J Virol. 2002 Dec;76(23):12394-8. doi: 10.1128/jvi.76.23.12394-12398.2002.
Abstract
Apolipoprotein E (ApoE), a constituent of the lipoproteins, may be relevant in herpes simplex virus type 1 (HSV-1) infection of the central nervous system (CNS), since HSV-1 binds to human serum ApoE lipoproteins. This study demonstrates the involvement of ApoE in the hematogenous route of HSV-1 to the CNS.
摘要
载脂蛋白E（ApoE）是脂蛋白的一种成分，可能与单纯疱疹病毒1型（HSV-1）感染中枢神经系统（CNS）有关，因为HSV-1可与人血清ApoE脂蛋白结合。本研究证明了ApoE在HSV-1经血行途径感染CNS过程中的作用。
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