Sun Shumei S, Schubert Christine M, Chumlea William Cameron, Roche Alex F, Kulin Howard E, Lee Peter A, Himes John H, Ryan Alan S
The Lifespan Health Research Center Departments of Community Health, Pediatrics, and Mathematics and Statistics, Wright State University, School of Medicine, Dayton, Ohio 45420, USA.
Pediatrics. 2002 Nov;110(5):911-9. doi: 10.1542/peds.110.5.911.
To provide clinically meaningful, normative reference data that describe the timing of sexual maturity indicators among a national sample of US children and to determine the degree of racial/ethnic differences in these estimates for each maturity indicator.
Tanner staging assessment of sexual maturity indicators was recorded from 4263 non-Hispanic white, black, and Mexican American girls and boys aged 8.00 to 19.00 years as part of the Third National Health and Nutrition Examination Survey (NHANES III) conducted between 1988 and 1994. NHANES III followed a complex, stratified, multistage probability cluster design. SUDAAN was used to calculate the mean age and standard error for each maturity stage and the proportion of entry into a maturity stage and to incorporate the sampling weight and design effects of the NHANES III complex sampling design. Probit analysis and median age at entry into a maturity stage and its fiducial limits were calculated using SAS 8.2.
Reference data for age at entry for maturity stages are presented in tabular and graphical format. Non-Hispanic black girls had an earlier sexual development for pubic hair and breast development either by median age at entry for a stage or for the mean age for a stage than Mexican American or non-Hispanic white girls. There were few to no significant differences between the Mexican American and non-Hispanic white girls. Non-Hispanic black boys also had earlier median and mean ages for sexual maturity stages than the non-Hispanic white and Mexican American boys.
Non-Hispanic black girls and boys mature early, but US children completed their sexual development at approximately the same ages. The present reference data for the timing of sexual maturation are recommended for the interpretation of assessments of sexual maturity in US children.
提供具有临床意义的规范性参考数据，描述美国儿童全国样本中性成熟指标的时间，并确定每个成熟指标在这些估计中的种族/族裔差异程度。
作为1988年至1994年进行的第三次全国健康和营养检查调查（NHANES III）的一部分，记录了4263名年龄在8.00至19.00岁之间的非西班牙裔白人、黑人以及墨西哥裔美国女孩和男孩的性成熟指标的坦纳分期评估。NHANES III采用了复杂的分层多阶段概率整群设计。使用SUDAAN计算每个成熟阶段的平均年龄和标准误差以及进入成熟阶段的比例，并纳入NHANES III复杂抽样设计的抽样权重和设计效应。使用SAS 8.2计算进入成熟阶段的概率分析和中位年龄及其置信限。
以表格和图形形式呈现了成熟阶段进入年龄的参考数据。非西班牙裔黑人女孩在阴毛和乳房发育方面的性发育，无论是按进入某个阶段的中位年龄还是该阶段的平均年龄，都比墨西哥裔美国女孩或非西班牙裔白人女孩更早。墨西哥裔美国女孩和非西班牙裔白人女孩之间几乎没有显著差异。非西班牙裔黑人男孩在性成熟阶段的中位年龄和平均年龄也比非西班牙裔白人男孩和墨西哥裔美国男孩更早。
非西班牙裔黑人女孩和男孩成熟较早，但美国儿童在大致相同的年龄完成性发育。建议使用目前关于性成熟时间的参考数据来解释美国儿童性成熟的评估。
