Murillo-Cortes J, Etayo-Perez A, Sebastian-Lopez C, Martino-Gorbea R, Rodriguez-Cortel J M
Servicio Cirugia Oral y Maxilofacial. Hospital Virgen del Camino, Pamplona, Spain.
Med Oral. 2002 Nov-Dec;7(5):370-4.
Although primary intraosseous carcinoma of the mandible is an uncommon lesion, they may not be as rare as generally believed. These tumours may, in theory, arise de novo from odontogenic remnants or from the malignant transformation of the lining of odontogenic cysts or tumours. Diagnosis based on histology and radiology is difficult. The prognosis is more favorable when PIOCs arise from odontogenic cysts. These tumors are locally aggressive and metastasize to regional nodes. The case study of a 70 year-old man with a primary intraosseous squamous carcinoma arising from a mandibular cyst is given.
尽管下颌骨原发性骨内癌是一种罕见的病变，但它们可能并不像普遍认为的那样罕见。从理论上讲，这些肿瘤可能起源于牙源性残余组织，或者由牙源性囊肿或肿瘤的内衬发生恶性转化而来。基于组织学和放射学进行诊断很困难。当原发性骨内癌起源于牙源性囊肿时，预后相对较好。这些肿瘤具有局部侵袭性，并会转移至区域淋巴结。本文给出了一名70岁男性下颌骨囊肿引发原发性骨内鳞状细胞癌的病例研究。
