De Caluwé D, Ahmed M, Puri P
The Children's Research Centre, Our Lady's Hospital for Sick Children, Crumlin 12, Dublin, Ireland.
Pediatr Surg Int. 2002 Sep;18(5-6):477-9. doi: 10.1007/s00383-002-0803-6. Epub 2002 Aug 23.
Thymic cysts are considered uncommon lesions in the differential diagnosis of pediatric neck masses. They usually present in the 1st decade after the age of 2 years, possibly because the thymus attains its greatest development before puberty. They may be found anywhere along the normal descent route of the thymus gland from the mandible to the sternal notch; 50% extend into the mediastinum. Most patients are asymptomatic, although respiratory complications may occur. A review of the operative records in our hospital over the last 10 years revealed two cases of cervical thymic cysts (CTC) in a 5- and a 9-year-old boy. Both children presented with an atraumatic, painless, enlarging mass in the left side of the neck anterior to the sternocleidomastoid muscle. Neither boy had respiratory problems or swallowing difficulties. Ultrasound and computed tomography showed a lesion consistent with a tentative diagnosis of a branchial cyst in one boy and an extensive cystic hygroma in the other. Both lesions were approached through a transverse cervical incision and, although closely adherent to the internal jugular vein, carotid artery, and vagus nerve, were resected completely. There were no postoperative complications and so far there has been no recurrence. CTCs are uncommon benign lesions that should be considered in the evaluation of neck masses in children. Preoperative diagnosis is unusual and, at this time, there is no preoperative radiologic test that can accurately identify a neck mass as a CTC. Histologic investigation of the excised specimen showing thymic tissue remnants with pathognomonic Hassall's corpuscles and cholesterol clefts in the cyst wall is the only definitive diagnosis. Evolution is benign. Intact, complete surgical excision remains the treatment of choice.
胸腺囊肿在小儿颈部肿块的鉴别诊断中被认为是不常见的病变。它们通常在2岁后的第一个十年出现,可能是因为胸腺在青春期前发育到最大程度。它们可能出现在胸腺从下颌骨到胸骨切迹的正常下降路径的任何位置;50%会延伸至纵隔。大多数患者无症状,尽管可能会发生呼吸系统并发症。回顾我院过去10年的手术记录,发现两名分别为5岁和9岁的男孩患有颈部胸腺囊肿(CTC)。两个孩子均表现为在胸锁乳突肌前方左侧颈部有无创、无痛、逐渐增大的肿块。两个男孩均无呼吸问题或吞咽困难。超声和计算机断层扫描显示,其中一个男孩的病变初步诊断为鳃裂囊肿,另一个男孩的病变为广泛的囊性水瘤。两个病变均通过颈部横切口进行处理,尽管它们与颈内静脉、颈动脉和迷走神经紧密粘连,但均被完全切除。术后无并发症,迄今为止也无复发。CTC是不常见的良性病变,在评估儿童颈部肿块时应予以考虑。术前诊断并不常见,目前尚无术前影像学检查能够准确将颈部肿块识别为CTC。对切除标本进行组织学检查,显示囊肿壁内有胸腺组织残余以及具有特征性的哈氏小体和胆固醇裂隙,这是唯一的确切诊断。其病程为良性。完整、彻底的手术切除仍然是首选的治疗方法。