Wagner C W, Vinocur C D, Weintraub W H, Golladay E S
University of Arkansas for Medical Sciences, Little Rock.
J Pediatr Surg. 1988 Jul;23(7):657-60. doi: 10.1016/s0022-3468(88)80640-7.
Thymic cysts are considered uncommon lesions in the differential diagnosis of pediatric neck masses. They have been described as asymptomatic and of little clinical consequence. Recent reports have stressed the possibility of respiratory compromise associated with these lesions. We reviewed our experience with cervical thymic cysts with emphasis on respiratory problems. Ten pediatric patients underwent surgery and were found to have cervical thymic cysts. Ages ranged from newborn to 14 years. There were four boys and six girls. Two were found to have the thymic cysts at time of neck exploration for Grave's disease and hyperparathyroidism. Of the remaining eight patients, all had mobile cystic masses, located anterior to but extending beneath the lower third of the sternocleidomastoid muscle. The size of the mass ranged from 3.0 to 8.5 cm. Preoperative diagnosis included cystic hygroma/branchial cleft cyst (five), lymphoma (one), teratoma (one), and thymic cyst (one). All had a history of rapidly developing neck mass. Seven of the eight gave a history of upper respiratory tract infection (URI) prior to the development of the mass. Five had imaging studies that showed tracheal compression. Three of these required airway management in the early postoperative period. All were excised through a neck incision, with two requiring sternal extension. Histology showed cholesterol crystals, Hassall's corpuscles, and giant cell reaction diagnosis of thymic cysts. There has been no recurrence and no permanent respiratory sequela in the ten patients. Cervical thymic cysts are benign lesions that may be more common than literature suggests.(ABSTRACT TRUNCATED AT 250 WORDS)
胸腺囊肿在小儿颈部肿块的鉴别诊断中被认为是罕见病变。它们被描述为无症状且临床意义不大。近期报告强调了这些病变与呼吸功能受损相关的可能性。我们回顾了我们在颈部胸腺囊肿方面的经验,重点关注呼吸问题。10例儿科患者接受了手术,被发现患有颈部胸腺囊肿。年龄范围从新生儿到14岁。有4名男孩和6名女孩。2例在因格雷夫斯病和甲状旁腺功能亢进进行颈部探查时发现有胸腺囊肿。在其余8例患者中,所有患者均有可活动的囊性肿块,位于胸锁乳突肌下三分之一的前方但延伸至其下方。肿块大小从3.0厘米至8.5厘米不等。术前诊断包括囊性水瘤/鳃裂囊肿(5例)、淋巴瘤(1例)、畸胎瘤(1例)和胸腺囊肿(1例)。所有患者都有颈部肿块迅速增大的病史。8例中有7例在肿块出现前有上呼吸道感染史。5例患者的影像学检查显示气管受压。其中3例在术后早期需要气道管理。所有患者均通过颈部切口切除,2例需要延长至胸骨。组织学显示胆固醇结晶、哈氏小体和巨细胞反应,诊断为胸腺囊肿。10例患者均无复发且无永久性呼吸后遗症。颈部胸腺囊肿是良性病变,可能比文献报道的更为常见。(摘要截短至250字)