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犬动脉瘤样骨囊肿的恶性转化

Malignant transformation of an aneurysmal bone cyst in a dog.

作者信息

Barnhart Matthew D

机构信息

MedVet Associates, Inc., Columbus, OH, USA.

出版信息

Vet Surg. 2002 Nov-Dec;31(6):519-24. doi: 10.1053/jvet.2002.36014.

DOI:10.1053/jvet.2002.36014
PMID:12415520
Abstract

OBJECTIVE

To report malignant transformation of an aneurysmal bone cyst in a dog.

STUDY DESIGN

Case report.

SAMPLE POPULATION

Client-owned dog.

RESULTS

A 5-year-old male Labrador retriever was diagnosed with an aneurysmal bone cyst of the distal aspect of the right ulna. Surgical curettage resulted in remission of clinical signs for 33 months. Because of recurrence of clinical signs, a distal ulnar ostectomy was performed. Histopathologic examination of the excised specimen revealed a moderately differentiated chondrosarcoma at the level of the bone cyst. Limb function was normal for 17 months until a subcutaneous mass, determined to be a chondrosarcoma, occurred at the level of the shoulder. A right forequarter amputation was performed.

CONCLUSIONS

Aneurysmal bone cysts are benign but may be transformed into a malignancy after surgical manipulation. Complete surgical excision should be attempted where possible. In this case, distal ulnar ostectomy was an effective means of preserving limb function and preventing local recurrence of chondrosarcoma.

摘要

目的

报告一例犬动脉瘤样骨囊肿的恶变情况。

研究设计

病例报告。

样本群体

客户拥有的犬。

结果

一只5岁雄性拉布拉多猎犬被诊断为右尺骨远端动脉瘤样骨囊肿。手术刮除术后临床症状缓解33个月。由于临床症状复发,进行了尺骨远端切除术。对切除标本的组织病理学检查显示,骨囊肿水平处为中度分化软骨肉瘤。肢体功能正常17个月,直到肩部出现一个皮下肿块,经确定为软骨肉瘤。遂进行了右前肢截肢术。

结论

动脉瘤样骨囊肿是良性的,但手术操作后可能恶变。应尽可能尝试完整手术切除。在本病例中,尺骨远端切除术是保留肢体功能和预防软骨肉瘤局部复发的有效方法。

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