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犬后肢的非骨骼多中心性软骨肉瘤

Non-skeletal multicentric chondrosarcoma in the hindlimb of a dog.

作者信息

Cohen Liat, Dank Gillian, Milgram Joshua

机构信息

Veterinary Teaching Hospital, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Israel.

出版信息

J Small Anim Pract. 2010 Oct;51(10):553-7. doi: 10.1111/j.1748-5827.2010.00977.x.

DOI:10.1111/j.1748-5827.2010.00977.x
PMID:21029099
Abstract

An eight-year-old, spayed, female golden retriever was presented with progressive right hindlimb lameness and polyuria/polydipsia. Multiple soft tissue masses were palpable within the hindlimb muscles. A tentative diagnosis of sarcoma was made on fine needle aspiration. A computed tomography scan of the hindlimb and thorax confirmed the presence and location of the masses, none of which were associated with the bones of the hindlimb. In addition, two pulmonary lesions were identified in the right cranial lung lobe. A diagnosis of chondrosarcoma was confirmed on histopathology with a final diagnosis of extraskeletal chondrosarcoma. A high, hindlimb amputation was performed, and chemotherapy was initiated. Polyuria and polydipsia resolved 2 weeks postoperatively. Numerous lung lesions, suspected to be metastases were found on routine followup radiographs, 73 days post surgery after which the dog was lost to follow-up.

摘要

一只八岁已绝育的雌性金毛猎犬出现右后肢进行性跛行和多尿/多饮症状。在后肢肌肉内可触及多个软组织肿块。细针穿刺初步诊断为肉瘤。后肢和胸部的计算机断层扫描证实了肿块的存在和位置,这些肿块均与后肢骨骼无关。此外,在右肺上叶发现了两个肺部病变。组织病理学确诊为软骨肉瘤,最终诊断为骨外软骨肉瘤。进行了高位后肢截肢,并开始化疗。术后两周多尿和多饮症状消失。术后73天的常规随访X光片上发现许多疑似转移的肺部病变,此后该犬失去随访。

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