Sanes J, Donovick P J, Burright R G
J Neurosci Res. 1975;1(5-6):333-41. doi: 10.1002/jnr.490010502.
Septal lesions or control operations were produced in male and female rats. Measurements of water and food consumption were carried out while the rats were housed under warm vivarium temperatures (24 degrees C) and when maintained in a cold room (6 degrees C). Examination of the data from the entire week spent in the cold revealed that rats with septal lesions deviated from precold water-comsumption levels less than comparable control rats. Further, whereas rats with septal lesions suppressed intake for the first 24 hr following either shift in environmental temperatures, control animals inhibited drinking only when returned to the warm environment. Both surgical groups elevated food consumption in the cold. The relative amount of food and water consumed during the day (vs night) increased for all groups when maintained in the cold. Differences in degree of reactivity to the manipulations were observed in male and female rats. These findings were interpreted as adding further support to our contention that septal lesions alter the behavioral (rather than direct metabolic) adaptations an animal makes to its environment.
对雄性和雌性大鼠进行了中隔损伤或对照手术。在大鼠饲养于温暖的饲养箱温度（24摄氏度）下以及饲养在寒冷房间（6摄氏度）时，对其水和食物消耗进行了测量。对在寒冷环境中度过的整整一周的数据检查显示，中隔损伤的大鼠与可比的对照大鼠相比，偏离冷前水消耗水平的程度更小。此外，虽然中隔损伤的大鼠在环境温度任何一种变化后的最初24小时内都会抑制摄入量，但对照动物只有在回到温暖环境时才会抑制饮水。两个手术组在寒冷环境中均增加了食物消耗。当饲养在寒冷环境中时，所有组白天（与夜晚相比）消耗的食物和水的相对量都增加了。在雄性和雌性大鼠中观察到了对这些操作的反应程度差异。这些发现被解释为进一步支持了我们的论点，即中隔损伤会改变动物对其环境所做出的行为（而非直接代谢）适应。
