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腹主动脉瘤的外科治疗:影响死亡率和发病率的因素——20年经验

Surgical management of abdominal aortic aneurysms: factors influencing mortality and morbidity--a 20-year experience.

作者信息

Thompson J E, Hollier L H, Patman R D, Persson A V

出版信息

Ann Surg. 1975 May;181(5):654-61. doi: 10.1097/00000658-197505000-00020.

Abstract

Abdominal aortic aneurysmectomy is being performed with progressively lower operative mortality and morbidity. Three hundred thirty seven patients have had elective aneurysm repair since 1954. Factors affecting mortality and morbidity in the last 108 cases are analyzed. Seventy-four per cent of patients had pre-existing disease, either cardiac, pulmonary, renal, cerebrovascular, diabetes mellitus, or hypertension. Six patients died following operation, a mortality rate of 5.5%. One died of pulmonary and 5 of cardiac causes. No patient died of renal failure or required dialysis. A signficant feature of management is the regimen of fluid therapy using dextrose in lactated Ringer's solution during and after operation to minimize hypotensive and renal complications. No patient developed a wound infection, graft infection, wound dehiscence, stroke, or intestinal ischemia. Serious postoperative complications were largely cardiac or pulmonary. Despite recent liberalization of indications for operation, comparative figures show continued reduction in operative mortality from 17% during 1954-1961, or 7.4% during 1962-1967, to 5.5% in the 1968-1974 era. This declining mortality is related to earlier diagnosis using non-invasive methods (sonogram), simplified operative techniques, improvement in fluid management, innovations in cardiopulmonary therapy, and recognition and proper handling of unusual manifestations of aortic aneurysms.

摘要

腹主动脉瘤切除术的手术死亡率和发病率正逐步降低。自1954年以来,已有337例患者接受了择期动脉瘤修复手术。对最近108例患者影响死亡率和发病率的因素进行了分析。74%的患者存在原有疾病,包括心脏、肺部、肾脏、脑血管、糖尿病或高血压。6例患者术后死亡,死亡率为5.5%。1例死于肺部疾病,5例死于心脏疾病。无患者死于肾衰竭或需要透析治疗。治疗的一个显著特点是在手术期间和术后使用含乳酸林格氏液的葡萄糖进行液体治疗方案,以尽量减少低血压和肾脏并发症。无患者发生伤口感染、移植物感染、伤口裂开、中风或肠缺血。严重的术后并发症主要是心脏或肺部并发症。尽管最近手术指征有所放宽,但对比数据显示手术死亡率持续下降,从1954 - 1961年期间的17%,或1962 - 1967年期间的7.4%,降至1968 - 1974年期间的5.5%。这种死亡率的下降与使用非侵入性方法(超声检查)进行早期诊断、简化手术技术、改善液体管理、心肺治疗的创新以及对主动脉瘤异常表现的认识和正确处理有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a667/1345559/a2c7b6a7bb9f/annsurg00291-0183-a.jpg

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