双侧丘脑胶质瘤——病例报告

Bilateral thalamic glioma--case report.

作者信息

Uchino Masafumi, Kitajima Satoru, Miyazaki Chikao, Shibata Iekado, Miura Myouta

机构信息

Department of Neurosurgery, Toho University School of Medicine, Tokyo, Japan.

出版信息

Neurol Med Chir (Tokyo). 2002 Oct;42(10):443-6. doi: 10.2176/nmc.42.443.

DOI:10.2176/nmc.42.443

PMID:12416569

Abstract

A 35-year-old woman presented with a bilateral thalamic glioma manifesting as dysesthesia over the left side of the body and mental deterioration. T1-weighted magnetic resonance imaging revealed enlarged bilateral thalami with homogeneous isointensity and no enhancement after gadolinium administration. Histological examination of a stereotactic biopsy specimen identified anaplastic astrocytoma. Radiotherapy and chemotherapy failed to arrest tumor growth. She subsequently died. Magnetic resonance imaging and clinical findings support the view that bilateral thalamic gliomas represent a distinct clinicopathologic entity among thalamic tumors.

摘要

一名35岁女性因双侧丘脑胶质瘤就诊，表现为身体左侧感觉异常和精神衰退。T1加权磁共振成像显示双侧丘脑增大，信号均匀等密度，注射钆后无强化。立体定向活检标本的组织学检查确诊为间变性星形细胞瘤。放疗和化疗未能阻止肿瘤生长。她随后死亡。磁共振成像和临床发现支持这样的观点，即双侧丘脑胶质瘤在丘脑肿瘤中代表一种独特的临床病理实体。