Single-breathhold 3D-trueFISP cine cardiac imaging.

Cardiac MRI function measurements are typically based on multiple breathhold 2D sequences to acquire images of the entire heart. In the present study, the feasibility of a cine 3D TrueFISP technique in which several complete volumetric measurements may be obtained during a single breathhold is demonstrated. In contrast to 3D FLASH, the TrueFISP sequence offers an excellent contrast between the myocardium and the intraventricular cavity without the use of contrast agent. An ECG-gated 3D cine TrueFISP sequence was implemented with a repetition time of 2.4-2.8 ms, which allows imaging of the complete heart within a single breathhold throughout 20-46 heartbeats with a 3D frame rate of 8-13 volumes per cardiac cycle and a spatial resolution of about 1.5 x 3.5 x 3.5 mm(3). Breathhold volumetric cine imaging with the 3D TrueFISP technique holds promise for rapid and accurate evaluation of the cardiac regional wall motion and the calculation of cardiac volume and ejection fraction.