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在双轴髋关节模拟器中,传统型和交联型超高分子量聚乙烯髋臼杯与抛光和粗糙的钴铬合金股骨头之间的磨损情况

Wear of conventional and cross-linked ultra-high-molecular-weight polyethylene acetabular cups against polished and roughened CoCr femoral heads in a biaxial hip simulator.

作者信息

Saikko Vesa, Calonius Olof, Keränen Jaakko

机构信息

Department of Mechanical Engineering, Helsinki University of Technology, P O Box 4300, FIN-02015 HUT, Finland.

出版信息

J Biomed Mater Res. 2002;63(6):848-53. doi: 10.1002/jbm.10471.

DOI:10.1002/jbm.10471
PMID:12418033
Abstract

The wear of acetabular cups made from conventional gamma-sterilized, and electron-beam cross-linked ultra-high-molecular-weight polyethylene was studied with a biaxial hip wear simulator. The femoral heads were either polished or roughened so that they represented the type of roughening and the value of surface roughness (R(a) = 0.14-0.18 micro m) observed in the roughest explanted femoral heads. The lubricant was diluted calf serum, and the test length 3 million cycles. The mean wear rate and standard deviation of conventional polyethylene cups against polished and against roughened heads was 11.6 +/- 0.07 and 64.4 +/- 10.1 mg per 1 million cycles, respectively. The latter value closely corresponds to that measured from explanted Charnley prostheses. Against polished heads, cross-linked polyethylene cups showed net weight gain, whereas against roughened heads, their mean wear rate was 2.4 +/- 0.3 mg per 1 million cycles. The mean equivalent circle diameters of polyethylene wear particles produced in the above four categories were: conventional/roughened 0.32 micro m, cross-linked/roughened 0.29 micro m, conventional/polished 0.28 micro m, cross-linked/polished 0.23 micro m. The size ranges and shapes were close to those seen in particles isolated from tissue samples. In conclusion, the tests indicated that electron-beam irradiation effectively reduces the harmful polyethylene wear particle production in total hip arthroplasty.

摘要

使用双轴髋关节磨损模拟器研究了由传统伽马灭菌和电子束交联的超高分子量聚乙烯制成的髋臼杯的磨损情况。股骨头经过抛光或粗糙化处理,以代表在最粗糙的取出股骨头中观察到的粗糙化类型和表面粗糙度值(R(a)=0.14 - 0.18微米)。润滑剂为稀释的小牛血清,测试时长为300万次循环。传统聚乙烯杯相对于抛光股骨头和粗糙股骨头的平均磨损率及标准差分别为每100万次循环11.6±0.07毫克和64.4±10.1毫克。后一数值与从取出的Charnley假体测量的值非常接近。相对于抛光股骨头,交联聚乙烯杯显示出净重增加,而相对于粗糙股骨头,其平均磨损率为每100万次循环2.4±0.3毫克。上述四类情况下产生的聚乙烯磨损颗粒的平均等效圆直径分别为:传统/粗糙0.32微米、交联/粗糙0.29微米、传统/抛光0.28微米、交联/抛光0.23微米。其尺寸范围和形状与从组织样本中分离出的颗粒相近。总之,测试表明电子束辐照可有效减少全髋关节置换术中有害聚乙烯磨损颗粒的产生。

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