Erdogan Bulent, Sen Orhan, Aydin M Volkan, Bagis Tayfun, Bavbek Murad
Departments of Neurosurgery and of Obstetrics and Gynecology, Başkent University Faculty of Medicine, Ankara, Turkey.
J Reprod Med. 2002 Oct;47(10):864-6.
The incidence of symptomatic hemangioblastoma of the posterior fossa during pregnancy is extremely low. Previous reports have noted that pregnancy seems to aggravate the clinical course of intracranial tumors, but little is known about the possible reasons. Various theories have been proposed to explain the rapid neurologic deterioration of hemangioblastoma patients during pregnancy; however, the pathophysiologic behavior and histogenesis of this vascular tumor are still not well understood.
A case of cerebellar hemangioblastoma was diagnosed during pregnancy. Urgent surgery was required due to rapid development of obstructive hydrocephalus and brainstem compression.
Obstetricians and neurosurgeons should be aware of the rare clinic entity of hemangioblastoma during pregnancy. Surgery might be indicated as soon as the tumor becomes symptomatic.
妊娠期后颅窝症状性血管母细胞瘤的发病率极低。既往报道指出,妊娠似乎会加重颅内肿瘤的临床进程,但对于其可能的原因知之甚少。人们提出了各种理论来解释血管母细胞瘤患者在妊娠期迅速出现的神经功能恶化;然而,这种血管肿瘤的病理生理行为和组织发生仍未得到充分了解。
一名妊娠期小脑血管母细胞瘤患者被诊断出来。由于梗阻性脑积水和脑干受压迅速发展,需要紧急手术。
产科医生和神经外科医生应了解妊娠期血管母细胞瘤这种罕见的临床实体。一旦肿瘤出现症状,可能就需要进行手术。