Marinelli William A, Leatherman James W
Division of Pulmonary and Critical Care Medicine, Hennepin County Medical Center, 701 Park Avenue, Minneapolis, MN 55415, USA.
Crit Care Clin. 2002 Oct;18(4):915-29, x. doi: 10.1016/s0749-0704(02)00020-9.
Neuromuscular disorders encountered in the ICU can be categorized as muscular diseases that lead to ICU admission and those that are acquired in the ICU. This article discusses three neuromuscular disorders can lead to ICU admission and have a putative immune-mediated pathogenesis: the Guillian-Barré syndrome, myasthenia gravis, and dermatomyositis/polymyositis. It also reviews critical care polyneuropathy and ICU acquired myopathy, two disorders that, alone or in combination, are responsible for nearly all cases of severe ICU acquired muscle weakness.
在重症监护病房（ICU）中遇到的神经肌肉疾病可分为两类：导致患者入住ICU的肌肉疾病以及在ICU中获得性的肌肉疾病。本文讨论了三种可导致患者入住ICU且具有假定免疫介导发病机制的神经肌肉疾病：吉兰-巴雷综合征、重症肌无力以及皮肌炎/多发性肌炎。本文还回顾了重症监护病房多发性神经病和ICU获得性肌病，这两种疾病单独或共同导致了几乎所有严重的ICU获得性肌无力病例。
