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重症疾病相关的神经肌肉疾病——要牢记它们。

Critical illness associated neuromuscular disorders -- keep them in mind.

作者信息

Nemes Réka, Molnár Levente, Fülep Zoltán, Fekete Kálra, Berhés Mariann, Fülesdi Béla

出版信息

Ideggyogy Sz. 2014 Nov 30;67(11-12):364-75.

PMID:25720238
Abstract

Neuromuscular disorders complicating sepsis and critical illness are not new and scarce phenomena yet they receive little attention in daily clinical practice. Critical illness polyneuropathy and myopathy affect nearly half of the patients with sepsis. The difficult weaning from the ventilator, the prolonged intensive care unit and hospital stay, the larger complication and mortality rate these disorders predispose to, put a large burden on the patient and the health care system. The aim of this review is to give an insight into the pathophysiological background, diagnostic possibilities and potential preventive and therapeutic measures in connection with these disorders to draw attention to their significance and underline the importance of preventive approach.

摘要

脓毒症和危重症并发的神经肌肉疾病并非新出现的罕见现象,但在日常临床实践中却很少受到关注。危重症多发性神经病和肌病影响了近一半的脓毒症患者。脱机困难、重症监护病房和住院时间延长、这些疾病易引发的更多并发症和更高死亡率,给患者和医疗保健系统带来了沉重负担。本综述的目的是深入了解这些疾病的病理生理背景、诊断可能性以及潜在的预防和治疗措施,以引起对其重要性的关注,并强调预防方法的重要性。

相似文献

1
Critical illness associated neuromuscular disorders -- keep them in mind.重症疾病相关的神经肌肉疾病——要牢记它们。
Ideggyogy Sz. 2014 Nov 30;67(11-12):364-75.
2
Neuromuscular complications of critical illness.危重病的神经肌肉并发症
Crit Care Clin. 2014 Oct;30(4):785-94. doi: 10.1016/j.ccc.2014.06.008. Epub 2014 Jul 30.
3
[Neuromuscular manifestations in critically ill patients].[危重症患者的神经肌肉表现]
Ugeskr Laeger. 2007 Jun 4;169(23):2216-9.
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The critical illness polyneuropathy in septic patients with prolonged weaning from mechanical ventilation: is the diaphragm also affected? A pilot study.脓毒症机械通气撤机困难患者的危重病性多发性神经病:膈肌是否也受影响?一项初步研究。
Respir Care. 2012 Oct;57(10):1594-601. doi: 10.4187/respcare.01396. Epub 2012 Mar 13.
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Clinical approach to the weak patient in the intensive care unit.重症监护病房中虚弱患者的临床处理方法
Respir Care. 2006 Sep;51(9):1024-40; discussion 1040-1.
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ICU-acquired weakness.重症监护病房获得性肌无力
Chest. 2007 May;131(5):1541-9. doi: 10.1378/chest.06-2065.
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[Intensive care unit-acquired weakness: development of polyneuropathy and myopathy in critically ill patients].[重症监护病房获得性肌无力:危重症患者多神经病和肌病的发生]
Brain Nerve. 2014 Feb;66(2):161-70.
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Critical illness neuromyopathy.危重病性神经肌肉病
Phys Med Rehabil Clin N Am. 2008 Feb;19(1):97-110, vii. doi: 10.1016/j.pmr.2007.10.012.
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Weakness on the intensive care unit.重症监护病房内的虚弱状况。
Pract Neurol. 2008 Oct;8(5):280-95. doi: 10.1136/jnnp.2008.157263.
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Electrophysiology of neuromuscular disorders in critical illness.危重病患者神经肌肉疾病的电生理学。
Muscle Nerve. 2013 Mar;47(3):452-63. doi: 10.1002/mus.23615. Epub 2013 Feb 6.

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