健康个体唾液中褪黑素浓度及免疫活性细胞血液含量的昼夜变化。

Circadian variations of melatonin concentration in saliva and blood content of immunocompetent cells in healthy individuals.

作者信息

Litvinenko G I, Shurlygina A V, Malysheva O A, Kudaeva O T, Shirinskii V S, Kozlov V A, Trufakin V A

机构信息

Institute of Clinical and Experimental Lymphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk.

出版信息

Bull Exp Biol Med. 2002 May;133(5):500-2. doi: 10.1023/a:1019882325663.

DOI:10.1023/a:1019882325663

PMID:12420073

Abstract

Salivary content of melatonin and parameters of the immune status were studied in young healthy individuals. Morning and evening levels of melatonin showed different correlations with some immunity parameters. It was assumed that the degree and type of correlation between the immune system and melatonin depend on the phase of circadian cycle, which should be considered during evaluation of immunoendocrine status.

摘要

对年轻健康个体的唾液褪黑素含量和免疫状态参数进行了研究。褪黑素的早晨和晚上水平与一些免疫参数呈现出不同的相关性。据推测，免疫系统与褪黑素之间相关性的程度和类型取决于昼夜节律周期的阶段，在评估免疫内分泌状态时应予以考虑。