Joki Tatsuhiro, Oi Shizuo, Babapour Baback, Kaito Nobuyoshi, Ohashi Kazuyoshi, Ebara Masaki, Kato Masataka, Abe Toshiaki
Department of Neurosurgery, Jikei University, School of Medicine, 3-25-8 Nishi-Shinbashi Minato-ku, Tokyo 105-8461, Japan.
Childs Nerv Syst. 2002 Nov;18(11):629-33. doi: 10.1007/s00381-002-0638-4. Epub 2002 Sep 28.
Total removal of the tumor is the most acceptable therapeutic modality in the management of craniopharyngioma; however, there are innumerable factors that can upset treatment plans. Unresectable lesions are often treated with gamma knife surgery (GKS). Reduction of the cystic volume is necessary, to decrease the area to be treated with GKS. An Ommaya reservoir system is usually placed during open surgery or by stereotactic access.
The authors use a neuroendoscope for safer and less invasive placement of the Ommaya reservoir into deep-seated cystic lesions. The cystic component is aspirated, and the Ommaya reservoir tube is precisely guided and placed into the cyst cavity under neuroendoscopic control with a newly developed two-burr-hole technique. This neuroendoscopic procedure could make it easier to reduce cystic volume prior to GKS as the final procedure. This technique may also be used for instillation of chemotherapeutic agents and for repeat aspirations, making the achievement of cystic control more likely. This type of neuroendoscopic management is a safe and effective procedure and could be considered as an alternative management technique for some stubborn cystic craniopharyngiomas.
肿瘤全切是颅咽管瘤治疗中最可接受的治疗方式;然而,有无数因素可能打乱治疗计划。不可切除的病变通常采用伽玛刀手术(GKS)治疗。减少囊肿体积是必要的,以减少GKS治疗的面积。Ommaya储液囊系统通常在开颅手术期间或通过立体定向穿刺放置。
作者使用神经内镜将Ommaya储液囊更安全、微创地放置到深部囊性病变中。抽吸囊性成分,在神经内镜控制下,采用新开发的双钻孔技术,将Ommaya储液囊管精确引导并放置到囊腔内。这种神经内镜手术可以使在作为最终手术的GKS之前更容易减少囊肿体积。该技术还可用于化疗药物的灌注和重复抽吸,使囊肿控制更有可能实现。这种神经内镜管理是一种安全有效的手术,可被视为一些顽固囊性颅咽管瘤的替代管理技术。