Bennett Julie, Erker Craig, Lafay-Cousin Lucie, Ramaswamy Vijay, Hukin Juliette, Vanan Magimairajan I, Cheng Sylvia, Coltin Hallie, Fonseca Adriana, Johnston Donna, Lo Andrea, Zelcer Shayna, Alvi Saima, Bowes Lynette, Brossard Josée, Charlebois Janie, Eisenstat David, Felton Kathleen, Fleming Adam, Jabado Nada, Larouche Valérie, Legault Geneviève, Mpofu Chris, Perreault Sébastien, Silva Mariana, Sinha Roona, Strother Doug, Tsang Derek S, Wilson Beverly, Crooks Bruce, Bartels Ute
Division of Neuro-Oncology, The Hospital for Sick Children, Toronto, ON, Canada.
Division of Pediatric Hematology/Oncology, IWK Health Centre, Halifax, NS, Canada.
Front Oncol. 2020 Dec 22;10:593192. doi: 10.3389/fonc.2020.593192. eCollection 2020.
Primary CNS tumors are the leading cause of cancer-related death in pediatrics. It is essential to understand treatment trends to interpret national survival data. In Canada, children with CNS tumors are treated at one of 16 tertiary care centers. We surveyed pediatric neuro-oncologists to create a national standard of practice to be used in the absence of a clinical trial for seven of the most prevalent brain tumors in children. This allowed description of practice across the country, along with a consensus. This had a multitude of benefits, including understanding practice patterns, allowing for a basis to compare in future research and informing Health Canada of the current management of patients. This also allows all children in Canada to receive equivalent care, regardless of location.
原发性中枢神经系统肿瘤是儿童癌症相关死亡的主要原因。了解治疗趋势对于解读全国生存数据至关重要。在加拿大,患有中枢神经系统肿瘤的儿童在16个三级护理中心之一接受治疗。我们对儿科神经肿瘤学家进行了调查,以制定一项全国性的实践标准,用于在缺乏针对儿童中七种最常见脑肿瘤的临床试验时使用。这使得能够描述全国范围内的实践情况,并达成共识。这有诸多益处,包括了解实践模式、为未来研究提供比较基础以及向加拿大卫生部通报患者的当前管理情况。这也使加拿大所有儿童,无论身处何地,都能获得同等的护理。