Wawrzynowicz-Syczewska Marta, Leonciuk Agnieszka, Jurczyk Krzysztof, Karpińska Ewa, Boroń-Kaczmarska Anna
Katedra i Klinika Chorób Zakaznych PAM w Szczecinie.
Pol Merkur Lekarski. 2002 Aug;13(74):100-2.
Increased incidence of hepatocellular carcinoma related to hepatitis C virus (HCV) infection has been noted recently. Only in year 2000 seven new cases of HCC in HCV-positive patients were diagnosed. In all cases liver tumors were found in cirrhotic patients and they were at advanced stage (multiple or large in size) precluding successful therapy. More than half of HCC cases related to HCV infection were connected with blood transfusion(s) in the past. Patients transfused a few decades ago should be screened for HCV infection and those with liver cirrhosis require careful and regular monitoring including ultrasound and a-fetoprotein examinations in order to detect focal lesions at less advanced stage making medical intervention possible.
最近已注意到丙型肝炎病毒(HCV)感染相关的肝细胞癌发病率有所增加。仅在2000年就诊断出7例HCV阳性患者的HCC新病例。在所有病例中,肝肿瘤均在肝硬化患者中发现,且处于晚期(多发或体积较大),无法进行成功治疗。过去,超过一半的与HCV感染相关的HCC病例与输血有关。几十年前接受输血的患者应进行HCV感染筛查,而肝硬化患者需要仔细且定期监测,包括超声和甲胎蛋白检查,以便在较早期阶段检测到局灶性病变,从而使医疗干预成为可能。