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[由假白喉棒状杆菌引起的肺炎,一个值得了解的实体]

[Pneumonia caused by Corynebacterium pseudodiphteriticum, an entity worth knowing].

作者信息

Aspiroz Sancho C, Agustín Berne A, Navarro Pardos C, Sañudo Blasco B, Teller Justes P

机构信息

Servicios de Microbiología, Hospital de Alcañiz, Teruel.

出版信息

An Med Interna. 2002 Sep;19(9):463-5.

Abstract

Respiratory infections are challenging for clinicians and new microbes or those considered previously as normal flora or less virulent forms seen responsible for some cases. Thus, the case reported here is a nosocomial pneumonia caused by Corynebacterium pseudodiphteriticum in a man suffering chronic obstructive pulmonary disease and resolved with cefotaxime. This microorganism is part of the oropharingeal bacterial flora and is therefore associated mainly with respiratory disease an less commonly with endocarditis, prostheses or wound infections. Susceptibility testing found uniform susceptibility to b-lactamases, aminoglycosides, rifampin and tetracycline. Susceptibility to ciprofloxacine is variable and resistance to macrolides (erythromycin and clindamycin) was frequent.

摘要

呼吸道感染对临床医生来说是一项挑战,新出现的微生物或者那些以前被认为是正常菌群或毒力较低的形式在某些病例中被发现是致病原因。因此,本文报道的病例是一名患有慢性阻塞性肺疾病的男性患者发生的由假白喉棒状杆菌引起的医院获得性肺炎,使用头孢噻肟治疗后痊愈。这种微生物是口咽部细菌菌群的一部分,因此主要与呼吸道疾病相关,较少与心内膜炎、假体或伤口感染相关。药敏试验发现对β-内酰胺酶、氨基糖苷类、利福平和四环素均敏感。对环丙沙星的敏感性存在差异,对大环内酯类(红霉素和克林霉素)耐药很常见。

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