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血液透析患者中杰氏棒状杆菌菌血症。

Corynebacterium jeikeium bacteremia in a hemodialyzed patient.

机构信息

First Department of Microbiology, Medical School, Aristotle University of Thessaloniki, 5 N. Haronda Street, Thessaloniki, Greece.

出版信息

Int J Infect Dis. 2010 Sep;14 Suppl 3:e265-8. doi: 10.1016/j.ijid.2009.11.008. Epub 2010 Feb 18.

Abstract

Corynebacterium jeikeium, frequently encountered in clinical specimens, is part of the normal skin flora. Nevertheless, a few cases of C. jeikeium bacteremia followed by severe clinical manifestations have been reported. C. jeikeium has been reported to cause endocarditis, septicemia, meningitis, pneumonia and osteomyelitis, along with soft tissue and trauma infections. Herein we describe a case of C. jeikeium bacteremia in Greece. The isolation of a coryneform bacterium from a clinical specimen should not immediately be considered a superinfection by the skin flora. Clinical and laboratory investigations are essential in order to evaluate such cases before applying appropriate treatment. On the other hand, the association of coryneform bacteria and disease should be critically investigated, with a thorough identification of the strain, ideally beyond the classical methods, at a specialized center.

摘要

棒状杆菌属,常从临床标本中检出,是正常皮肤菌群的一部分。然而,有少数棒状杆菌属菌血症的报道,随后出现严重的临床表现。棒状杆菌属已被报道可引起心内膜炎、败血症、脑膜炎、肺炎和骨髓炎,以及软组织和创伤感染。本文描述了希腊的一例棒状杆菌属菌血症。从临床标本中分离出棒状杆菌属不应立即被认为是皮肤菌群的继发感染。临床和实验室检查对于评估此类病例非常重要,以便在应用适当的治疗方法之前进行评估。另一方面,应仔细研究棒状杆菌属与疾病的关系,并在专门中心进行彻底的菌株鉴定,理想情况下超越经典方法。

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