Puerto Alonso J L, García-Martos P, Girón González J A
Servicios de Microbiología, Hospital Universitario Puerta del Mar. Cádiz.
An Med Interna. 2002 Sep;19(9):473-6.
Arcanobacterium haemolyticum is a grampositive rod wich belonged, until a short time ago, to Corynebacterium genus, and recently classified in a new genus, with only one specie. Human is the main reservoir. It has been isolated from the skin and pharinx of healthy individuals, but also it is cause of infection, specially pharingitis, in children, and chronic cutaneous ulcus, in diabetic patients. Less frequently, it is cause of osteomyelitis, meningitis, pneumonia, abscess, endocarditis and sepsis. Diagnosis is difficult because its double quality: comensal and pathogen. There are not established guidelines for the treatment of these infections, although most of isolated strains are susceptibles to penicillin, erythromicin, clindamycin and tetracycline. High doses of penicillin, with or without gentamicin, it is recommended for the treatment of deep infections.
溶血隐秘杆菌是一种革兰氏阳性杆菌,直到不久前还属于棒状杆菌属,最近被归类到一个新属,且只有一个种。人类是主要储存宿主。它已从健康个体的皮肤和咽部分离出来,但也是儿童感染特别是咽炎以及糖尿病患者慢性皮肤溃疡的病因。较少见的情况下,它是骨髓炎、脑膜炎、肺炎、脓肿、心内膜炎和败血症的病因。诊断困难,因为它具有共生菌和病原体的双重性质。对于这些感染的治疗尚无既定指南,尽管大多数分离菌株对青霉素、红霉素、克林霉素和四环素敏感。推荐使用高剂量青霉素,可加或不加庆大霉素,用于治疗深部感染。