Sari R, Bayindir Y, Sevinc A, Bahceci F, Ozen S
Inonu University, School of Medicine, Department of Internal Medicine, Antalya, Turkey.
J Chemother. 2002 Aug;14(4):420-2. doi: 10.1179/joc.2002.14.4.420.
Extrapulmonary tuberculosis is known to be the infection in an organ with or without pulmonary involvement. The infection in extrapulmonary tuberculosis is insidious and the symptoms and signs are generally nonspecific. We describe a 56-year-old male patient complaining of weight loss, fever, and night sweats. Although there were no signs and symptoms attributable to pulmonary tuberculosis, polymerase chain reaction (PCR), microscobical and cultural examination of bone marrow aspirate revealed isolated bone marrow tuberculosis. A treatment protocol of isoniazid, rifampicin, pyrazinamide, and streptomycin was administered. After 9 months of treatment, re-examination of the bone marrow revealed no signs of tuberculosis. Tuberculosis should be kept in mind especially in endemic areas and bone marrow should be examined in case of suspected tuberculosis infection.
肺外结核是指在有或无肺部受累情况下发生在某一器官的感染。肺外结核感染隐匿,症状和体征通常无特异性。我们描述了一名56岁男性患者,主诉体重减轻、发热和盗汗。尽管没有肺结核的体征和症状,但骨髓穿刺液的聚合酶链反应(PCR)、显微镜检查和培养显示为孤立性骨髓结核。给予异烟肼、利福平、吡嗪酰胺和链霉素的治疗方案。治疗9个月后,骨髓复查未发现结核迹象。特别是在流行地区,应考虑到结核病,如怀疑有结核感染,应检查骨髓。