Suppr超能文献

种族:预测变量还是代理变量?脊髓损伤后的结果

Race: predictor versus proxy variable? Outcomes after spinal cord injury.

作者信息

Putzke John David, Hicken Bret L, Richards J Scott

机构信息

Department of Physical Medicine and Rehabilitation, University of Alabama, 1717 6th Avenue S, Birmingham, AL 35233-7330, USA.

出版信息

Arch Phys Med Rehabil. 2002 Nov;83(11):1603-11. doi: 10.1053/apmr.2002.35115.

Abstract

OBJECTIVE

To examine the impact of race on acute, rehabilitation, and long-term outcomes after spinal cord injury (SCI).

DESIGN

Two case control studies (study 1: acute and rehabilitation outcomes, study 2: long-term outcomes) in which white and nonwhite individuals were matched case for case on multiple demographic, medical, and geographic characteristics with the rationale being that a case-control methodology would increase the internal validity of the design, thereby increasing confidence in the assertion that any between-group differences observed may be specifically attributed to race.

SETTING

Data drawn from the Spinal Cord Injury Model Systems. Institutional practice and general community.

PARTICIPANTS

Study 1: 187 pairs of individuals, study 2: 158 pairs of matched individuals.

INTERVENTIONS

Not applicable.

MAIN OUTCOME MEASURES

Outcome measures assessed included economic (eg, cost of care), treatment-related (eg, length of hospital stay), functional (eg, FIM instrument), and medical (eg, number of medical complications) variables, as well as self-reported life satisfaction, level of handicap, and mental and physical health.

RESULTS

In study 1, none of the outcome measures differed significantly across racial groups. Similarly, study 2 failed to indicate significant differences in any of the outcome variables across racial groups, with the exception that nonwhites were at increased risk of greater self-reported handicap in the area of mobility. Power analyses indicated these finding were not merely the result of inadequate power.

CONCLUSION

For the outcomes assessed in studies 1 and 2, race appeared to act primarily as a proxy for other variables (eg, injury severity, age, educational achievement), which in turn may be associated with poor outcome after SCI. Theoretical implications and recommendations are discussed.

摘要

目的

探讨种族对脊髓损伤(SCI)后急性、康复及长期预后的影响。

设计

两项病例对照研究(研究1:急性和康复预后;研究2:长期预后),将白人和非白人个体按病例逐一匹配多项人口统计学、医学和地理特征,理由是病例对照方法可提高设计的内部效度,从而增强对以下论断的信心,即观察到的组间差异可能具体归因于种族。

背景

数据取自脊髓损伤模型系统。机构实践和普通社区。

参与者

研究1:187对个体;研究2:158对匹配个体。

干预措施

不适用。

主要结局指标

评估的结局指标包括经济(如护理费用)、治疗相关(如住院时间)、功能(如FIM量表)和医学(如医疗并发症数量)变量,以及自我报告的生活满意度、残疾程度和身心健康状况。

结果

在研究1中,各种族组间的结局指标均无显著差异。同样,研究2也未显示各种族组在任何结局变量上存在显著差异,只是非白人在行动能力方面自我报告的残疾程度较高的风险增加。效能分析表明,这些发现并非仅仅是效能不足的结果。

结论

对于研究1和研究2中评估的结局,种族似乎主要是其他变量(如损伤严重程度、年龄、教育程度)的替代指标,而这些变量反过来可能与SCI后的不良预后相关。讨论了理论意义和建议。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验