Phadke Shruti M, Chini Barbara A, Patton Donna, Goyal Rakesh K
Division of Pulmonology, Department of Pediatrics, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania 15116, USA.
Pediatr Pulmonol. 2002 Dec;34(6):488-90. doi: 10.1002/ppul.10192.
Pulmonary relapse of non-Hodgkin's lymphoma (NHL) occurred in a 10-year-old girl who presented with cough, blood-tinged sputum, and chest tightness. The diagnosis of Ki-1 (CD30) anaplastic large-cell lymphoma was established using bronchoalveolar lavage (BAL) and transbronchial biopsy (TBB). These procedures demonstrated malignant cells that stained positive for CD30 and had the t(2;5) translocation, thereby avoiding the need for an open lung biopsy.
一名10岁女孩出现咳嗽、痰中带血和胸闷症状,被诊断为非霍奇金淋巴瘤(NHL)肺部复发。通过支气管肺泡灌洗(BAL)和经支气管活检(TBB)确诊为Ki-1(CD30)间变性大细胞淋巴瘤。这些检查发现了CD30染色阳性且有t(2;5)易位的恶性细胞,从而避免了进行开胸肺活检。