Schwacha H
Abt. Innere Medizin II, Universitätsklinikum Freiburg.
Praxis (Bern 1994). 2002 Oct 9;91(41):1687-90. doi: 10.1024/0369-8394.91.41.1687.
Coeliac disease is an inflammatory disease of the small intestine. Coeliac disease occurs in individuals suffering from a genetically caused gluten intolerance. Mean clinical findings are malabsorption for several nutrients or steatorrhoe. Silent or latent courses are common. The diagnosis is based upon the histological finding of villous atrophy in duodenal or jejunal biopsies. Anti-endomysium-antibodies are of high sensitivity and specificity. After gluten free diet the coeliac disease improves. Gluten free diet has to be taken lifelong preventing complications i.e. osteoporosis and malignancies.
乳糜泻是一种小肠的炎症性疾病。乳糜泻发生在患有基因导致的麸质不耐受的个体中。常见的临床症状是多种营养素吸收不良或脂肪泻。无症状或潜伏病程很常见。诊断基于十二指肠或空肠活检中绒毛萎缩的组织学发现。抗肌内膜抗体具有高敏感性和特异性。采用无麸质饮食后，乳糜泻病情会改善。必须终身采用无麸质饮食以预防并发症，如骨质疏松症和恶性肿瘤。
