Barishak Y R, Beemer A M, Egyed M N, Shlosberg A, Eilat A
Acta Ophthalmol (Copenh). 1975 Sep;53(4):585-90. doi: 10.1111/j.1755-3768.1975.tb01777.x.
Geese and ducks were photosensitized by the ingestion of Ammi majus seeds, and exposure to sunlight. Mydriasis was a characteristic clinical feature of this syndrome in both species. Histologically the iris of the affected birds showed vacuolisation and varying degrees of atrophy of the muscle of the sphincter pupillae. The effect of pilocarpine and physostigmine on the normal and mydriatic eyes was studied. The possible mode of action of photosensitization and the significance of these findings in the light of the use of psoralens in human medicine is discussed.
鹅和鸭因摄入白花草种子并暴露于阳光下而发生光敏反应。瞳孔散大是这两个物种该综合征的特征性临床特征。组织学上，患病鸟类的虹膜显示瞳孔括约肌肌肉出现空泡化和不同程度的萎缩。研究了毛果芸香碱和毒扁豆碱对正常眼和散瞳眼的作用。讨论了光敏反应可能的作用方式以及根据补骨脂素在人类医学中的应用对这些发现的意义。
