Thorburn A W, Proietto J
Department of Medicine, University of Melbourne, Royal Melbourne Hospital, Victoria, Australia.
P N G Med J. 2001 Sep-Dec;44(3-4):111-23.
The aetiology of type 2 diabetes is still poorly understood. Although it is clear that obesity is a risk factor for the disease, obesity leads to diabetes only in susceptible individuals. Both genetic and environmental factors determine this susceptibility. This review describes the emerging evidence that low birthweight caused by malnutrition or a genetic predisposition increases the risk of type 2 diabetes.
2型糖尿病的病因仍未得到充分了解。虽然肥胖显然是该疾病的一个风险因素，但肥胖仅在易感个体中导致糖尿病。遗传和环境因素都决定了这种易感性。这篇综述描述了新出现的证据，即由营养不良或遗传易感性导致的低出生体重会增加2型糖尿病的风险。
