Evans T W
Department of Intensive Care Medicine, Imperial College of Science, Technology & Medicine, Clinical Director of ICU, Royal Brompton Hospital, London, UK.
Aliment Pharmacol Ther. 2002 Dec;16 Suppl 5:6-11. doi: 10.1046/j.1365-2036.16.s5.2.x.
Albumin is the main determinant of plasma oncotic pressure and it plays a pivotal role in modulating the distribution of fluids between compartments. Moreover, it has many other biological properties which may be important not only for its physiological actions but also for its therapeutic effects. Among the non-oncotic properties are its capacity of molecule transportation and free radical scavenging, its ability to modulate capillar permeability, neutrophil adhesion and activation and its haemostatic effects. The following article reviews these biological effects as well as its structure, synthesis, catabolism and distribution.
白蛋白是血浆胶体渗透压的主要决定因素，在调节不同腔隙间液体分布方面发挥着关键作用。此外，它还具有许多其他生物学特性，这些特性不仅对其生理作用很重要，对其治疗效果也很重要。在非胶体渗透压特性中，有其分子运输和自由基清除能力、调节毛细血管通透性、中性粒细胞黏附和活化的能力以及止血作用。以下文章综述了这些生物学效应以及其结构、合成、分解代谢和分布。
