• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一场完美风暴:慢性白蛋白丢失、多种疾病并存与抗生素耐药病例

A Perfect Storm: Case of Chronic Albumin Loss, Multi-Morbidity and Antibiotic Resistance.

作者信息

Snehasis Nayak, Zafar Sayed

机构信息

Medicine, University of Visayas Gullas college of Medicine, Banilad, Cebu, 6000, Philippines.

出版信息

Curr Health Sci J. 2024 Oct-Dec;50(5):607-611. doi: 10.12865/CHSJ.50.04.15. Epub 2024 Dec 31.

DOI:10.12865/CHSJ.50.04.15
PMID:40143879
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11936067/
Abstract

Comorbidity is described as the presence of many health disorders in one individual, which may be connected or arise independently. We report a 61-year-old male patient with a complex history of recurrent deep vein thrombosis (DVT) and chronic hypoalbuminemia presenting to the emergency department due to sudden left lower limb swelling, pain, coldness, and bluish discoloration of the foot, leading to a severe infection necessitating a below-knee amputation. Even after extensive workup, the etiology behind hypoalbuminemia remained unknown with Protein-losing enteropathy (PLE) suspected, but not confirmed. This is a very peculiar case and highlights the challenges in managing such patients while emphasizing the need for a multidisciplinary approach in long-term care.

摘要

共病是指一个人存在多种健康问题,这些问题可能相互关联或独立出现。我们报告了一名61岁男性患者,他有复发性深静脉血栓形成(DVT)和慢性低白蛋白血症的复杂病史,因左下肢突然肿胀、疼痛、发冷和足部发蓝而到急诊科就诊,导致严重感染,需要进行膝下截肢。即使经过广泛检查,低白蛋白血症的病因仍不清楚,怀疑是蛋白丢失性肠病(PLE),但未得到证实。这是一个非常特殊的病例,突出了管理此类患者的挑战,同时强调了长期护理中多学科方法的必要性。

相似文献

1
A Perfect Storm: Case of Chronic Albumin Loss, Multi-Morbidity and Antibiotic Resistance.一场完美风暴:慢性白蛋白丢失、多种疾病并存与抗生素耐药病例
Curr Health Sci J. 2024 Oct-Dec;50(5):607-611. doi: 10.12865/CHSJ.50.04.15. Epub 2024 Dec 31.
2
[Protein losing enteropathy (PLE) detected by Tc99m-labelled human serum albumin abdominal scintigraphy--case report].[通过Tc99m标记的人血清白蛋白腹部闪烁扫描检测到的蛋白丢失性肠病(PLE)——病例报告]
Przegl Lek. 2003;60(9):606-8.
3
Protein-losing enteropathy in ulcerative colitis.溃疡性结肠炎中的蛋白丢失性肠病
Case Rep Gastroenterol. 2012 Jan;6(1):177-82. doi: 10.1159/000338191. Epub 2012 Apr 11.
4
Protein-Losing Enteropathy as the First Presentation of Systemic Lupus Erythematosus in a Resource-Limited Setting in Sri Lanka: A Case Report.蛋白质丢失性肠病作为系统性红斑狼疮在斯里兰卡资源有限环境中的首发表现:一例报告
Cureus. 2023 Mar 24;15(3):e36619. doi: 10.7759/cureus.36619. eCollection 2023 Mar.
5
Rare Case of Unilateral Phlegmasia Cerulea Dolens With Bilateral Deep Vein Thrombosis at a Community Military Hospital Emergency Department.社区军事医院急诊科单侧股青肿合并双侧深静脉血栓形成的罕见病例
Mil Med. 2017 May;182(5):e1823-e1825. doi: 10.7205/MILMED-D-16-00346.
6
Phlegmasia Cerulea Dolens: A Rare Case Report.股青肿:一例罕见病例报告。
Adv Biomed Res. 2020 Jul 27;9:31. doi: 10.4103/abr.abr_3_20. eCollection 2020.
7
Successful management of portal vein thrombosis in a Yorkshire Terrier with protein-losing enteropathy.成功治疗一只约克夏梗的蛋白丢失性肠病伴门静脉血栓。
BMC Vet Res. 2020 Nov 2;16(1):418. doi: 10.1186/s12917-020-02632-9.
8
Case Report: Protein-Losing Enteropathy in Association With Tuberculosis-Related Constrictive Pericarditis.病例报告:与结核相关的缩窄性心包炎伴发的蛋白丢失性肠病
Front Pediatr. 2022 May 30;10:875032. doi: 10.3389/fped.2022.875032. eCollection 2022.
9
Right Lower Extremity Phlegmasia Cerulea Dolens Due to Iliotibial Vein Thrombosis With Compartment Syndrome and Circulatory Shock: Case Report and Review.因髂胫静脉血栓形成伴骨筋膜室综合征和循环休克导致的右下肢股青肿:病例报告及文献复习
Cureus. 2022 Dec 9;14(12):e32364. doi: 10.7759/cureus.32364. eCollection 2022 Dec.
10
Protein-losing enteropathy in systemic lupus erythematosus: analysis of the clinical features of fifteen patients.系统性红斑狼疮中的蛋白丢失性肠病:15例患者临床特征分析
J Clin Rheumatol. 2007 Dec;13(6):313-6. doi: 10.1097/RHU.0b013e31815bf9c6.

本文引用的文献

1
Hypoalbuminemia as predictor of thrombotic events in patients with community-acquired pneumonia.低白蛋白血症可预测社区获得性肺炎患者的血栓事件。
Int J Cardiol. 2024 Jun 1;404:131942. doi: 10.1016/j.ijcard.2024.131942. Epub 2024 Mar 7.
2
Albumin Levels and Risk of Early Cardiovascular Complications After Ischemic Stroke: A Propensity-Matched Analysis of a Global Federated Health Network.白蛋白水平与缺血性脑卒中后早期心血管并发症风险:全球联邦健康网络的倾向评分匹配分析。
Stroke. 2024 Mar;55(3):604-612. doi: 10.1161/STROKEAHA.123.044248. Epub 2024 Feb 7.
3
Novel insights about albumin in cardiovascular diseases: Focus on heart failure.
关于心血管疾病中白蛋白的新见解:关注心力衰竭。
Mass Spectrom Rev. 2023 Jul-Aug;42(4):1113-1128. doi: 10.1002/mas.21743. Epub 2021 Nov 8.
4
Genetically determined hypoalbuminemia as a risk factor for hypertension: instrumental variable analysis.遗传决定的低白蛋白血症是高血压的一个危险因素:工具变量分析。
Sci Rep. 2021 May 28;11(1):11290. doi: 10.1038/s41598-021-89775-3.
5
Hypoalbuminemia as Surrogate and Culprit of Infections.低白蛋白血症:感染的替代指标和致病因素。
Int J Mol Sci. 2021 Apr 26;22(9):4496. doi: 10.3390/ijms22094496.
6
Clostridium difficile Infection Following Spine Surgery: Incidence, Risk Factors, and Association With Preoperative Antibiotic Use.脊柱手术后艰难梭菌感染:发生率、危险因素及与术前抗生素使用的关系。
Spine (Phila Pa 1976). 2020 Nov 15;45(22):1572-1579. doi: 10.1097/BRS.0000000000003627.
7
LDL induces cholesterol loading and inhibits endothelial proliferation and angiogenesis in Matrigels: correlation with impaired angiogenesis during wound healing.LDL 诱导胆固醇负荷,抑制 Matrigels 中的内皮细胞增殖和血管生成:与伤口愈合过程中血管生成受损相关。
Am J Physiol Cell Physiol. 2020 Apr 1;318(4):C762-C776. doi: 10.1152/ajpcell.00495.2018. Epub 2020 Jan 29.
8
Hypoalbuminemia remains an independent predictor of complications following total joint arthroplasty.低蛋白血症仍然是全关节置换术后并发症的独立预测指标。
J Orthop. 2019 May 1;16(6):552-558. doi: 10.1016/j.jor.2019.04.019. eCollection 2019 Nov-Dec.
9
Preventive aspects in peripheral artery disease.外周动脉疾病的预防方面
Ther Adv Cardiovasc Dis. 2012 Apr;6(2):53-70. doi: 10.1177/1753944712437359. Epub 2012 Feb 15.
10
Antimicrobial therapy in critically ill patients: a review of pathophysiological conditions responsible for altered disposition and pharmacokinetic variability.重症患者的抗菌治疗:对导致药物处置改变和药代动力学变异性的病理生理状况的综述。
Clin Pharmacokinet. 2005;44(10):1009-34. doi: 10.2165/00003088-200544100-00002.