Luft F C, Walker P D, Hamburger R J, Kleit S A
JAMA. 1975 Dec 15;234(11):1158-60.
Renal vein thrombosis caused the nephrotic syndrome in a patient with morbid obesity. Pulmonary embolism occurred initially, but not after anticoagulants were administered. Surviving for three years, the patient died of profound uremia and hyperosmolar coma. At autopsy, membranous glomerular changes were found. Conclusive exclusion of renal vein thrombosis in the morbidly obese patient with nephrotic syndrome appears advisable.
肾静脉血栓形成导致一名病态肥胖患者出现肾病综合征。最初发生了肺栓塞,但在给予抗凝剂后未再发生。患者存活三年,死于严重尿毒症和高渗性昏迷。尸检时发现有膜性肾小球改变。对于患有肾病综合征的病态肥胖患者,似乎有必要明确排除肾静脉血栓形成。