生长激素释放激素（GHRH）与GHRH受体。 - Suppr

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超能文献

Growth Hormone Releasing Hormone (GHRH) and the GHRH Receptor.

作者信息

Lin-Su Karen, Wajnrajch Michael P

机构信息

Division of Pediatric Endocrinology, Weill Medical College of Cornell University, New York, USA.

出版信息

Rev Endocr Metab Disord. 2002 Dec;3(4):313-23. doi: 10.1023/a:1020949507265.

DOI:10.1023/a:1020949507265

PMID:12424433

Abstract

摘要

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Regulational effect of ghrelin on growth hormone secretion from perifused rat anterior pituitary cells.胃饥饿素对大鼠垂体前叶细胞灌流生长激素分泌的调节作用。

J Neuroendocrinol. 2002 Feb;14(2):156-62. doi: 10.1046/j.0007-1331.2001.00757.x.

Direct modification of somatotrope function by long-term leptin treatment of primary cultured ovine pituitary cells.通过长期用瘦素处理原代培养的绵羊垂体细胞直接改变生长激素细胞功能。

Endocrinology. 2001 Dec;142(12):5167-71. doi: 10.1210/endo.142.12.8559.

A low dose of ghrelin stimulates growth hormone (GH) release synergistically with GH-releasing hormone in humans.低剂量的胃饥饿素可与生长激素释放激素协同刺激人体生长激素（GH）的释放。

J Clin Endocrinol Metab. 2001 Sep;86(9):4552. doi: 10.1210/jcem.86.9.8002.

Regulation of the ghrelin gene: growth hormone-releasing hormone upregulates ghrelin mRNA in the pituitary.胃饥饿素基因的调控：生长激素释放激素上调垂体中的胃饥饿素mRNA。

Endocrinology. 2001 Sep;142(9):4154-7. doi: 10.1210/endo.142.9.8492.

Growth hormone (GH) secretion in patients with an inactivating defect of the GH-releasing hormone (GHRH) receptor is pulsatile: evidence for a role for non-GHRH inputs into the generation of GH pulses.生长激素释放激素（GHRH）受体存在失活缺陷的患者，其生长激素（GH）分泌呈脉冲式：这表明非GHRH输入在GH脉冲产生中发挥作用。

J Clin Endocrinol Metab. 2001 Jun;86(6):2459-64. doi: 10.1210/jcem.86.6.7536.

Isolated growth hormone (GH) deficiency due to compound heterozygosity for two new mutations in the GH-releasing hormone receptor gene.由于生长激素释放激素受体基因中的两个新突变导致的复合杂合性引起的孤立性生长激素缺乏症。

Clin Endocrinol (Oxf). 2001 May;54(5):681-7. doi: 10.1046/j.1365-2265.2001.01273.x.

Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway.胃饥饿素是一种内源性生长激素促分泌素，是一种新型的食欲肽，它通过激活下丘脑神经肽Y/Y1受体途径拮抗瘦素作用。

Diabetes. 2001 Feb;50(2):227-32. doi: 10.2337/diabetes.50.2.227.

Three new mutations in the gene for the growth hormone (gh)-releasing hormone receptor in familial isolated gh deficiency type ib.家族性孤立性生长激素（GH）缺乏症ib型中生长激素释放激素受体基因的三个新突变。

J Clin Endocrinol Metab. 2001 Jan;86(1):273-9. doi: 10.1210/jcem.86.1.7156.

Arginine counteracts the inhibitory effect of recombinant human insulin-like growth factor I on the somatotroph responsiveness to growth hormone-releasing hormone in humans.精氨酸可抵消重组人生长激素释放因子对人类生长激素释放激素促生长反应的抑制作用。

J Clin Endocrinol Metab. 2000 Oct;85(10):3604-8. doi: 10.1210/jcem.85.10.6872.

Secretagogues and the somatotrope: signaling and proliferation.促分泌素与生长激素细胞：信号传导与增殖

Recent Prog Horm Res. 2000;55:269-90; discussion 290-1.

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