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Insulin-like growth factor (IGF)-I gene deletion.

作者信息

Camacho-Hübner Cecilia, Woods Katie A, Clark Adrian J L, Savage Martin O

机构信息

Paediatric Endocrinology Section, Department of Endocrinology, St. Bartholomew's Hospital, London, UK.

出版信息

Rev Endocr Metab Disord. 2002 Dec;3(4):357-61. doi: 10.1023/a:1020957809082.

DOI:10.1023/a:1020957809082
PMID:12424437
Abstract
摘要

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Insulin-like growth factor (IGF)-I gene deletion.胰岛素样生长因子（IGF）-I基因缺失。
Rev Endocr Metab Disord. 2002 Dec;3(4):357-61. doi: 10.1023/a:1020957809082.
2
Experience with insulin-like growth factor I (IGF-I) treatment of growth hormone insensitivity syndrome (GHIS).胰岛素样生长因子I（IGF-I）治疗生长激素不敏感综合征（GHIS）的经验。
J Pediatr Endocrinol Metab. 1999 Apr;12 Suppl 1:259-66.
3
Insulin-like growth factor-I deficiency caused by a partial deletion of the IGF-I gene: effects of rhIGF-I therapy.因胰岛素样生长因子-I（IGF-I）基因部分缺失导致的IGF-I缺乏：重组人IGF-I治疗的效果
Growth Horm IGF Res. 1999 Jun;9 Suppl B:47-51; discussion 51-2. doi: 10.1016/s1096-6374(99)80081-1.
4
Insulin-like growth factor-I treatment of growth disorders, diabetes mellitus and insulin resistance.胰岛素样生长因子-I治疗生长障碍、糖尿病和胰岛素抵抗。
Trends Endocrinol Metab. 2005 May-Jun;16(4):190-7. doi: 10.1016/j.tem.2005.03.011.
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6
In vitro and in vivo responses to short-term recombinant human insulin-like growth factor-1 (IGF-I) in a severely growth-retarded girl with ring chromosome 15 and deletion of a single allele for the type 1 IGF receptor gene.
Clin Endocrinol (Oxf). 1999 Nov;51(5):541-50. doi: 10.1046/j.1365-2265.1999.00799.x.
7
Effects of recombinant human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion.重组人胰岛素样生长因子I（IGF-I）治疗对一名部分IGF-I基因缺失患者生长激素-IGF系统的影响。
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Insulin-like growth factor I gene deletion causing intrauterine growth retardation and severe short stature.胰岛素样生长因子I基因缺失导致宫内生长迟缓及严重身材矮小。
Acta Paediatr Suppl. 1997 Nov;423:39-45. doi: 10.1111/j.1651-2227.1997.tb18367.x.

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Mechanisms of action of brain insulin against neurodegenerative diseases.脑胰岛素对抗神经退行性疾病的作用机制。
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本文引用的文献

1
Growth hormone insensitivity: pathophysiology, diagnosis, clinical variation and future perspectives.
Horm Res. 2001;55 Suppl 2:32-5. doi: 10.1159/000063471.
2
Insulin-like growth factor -I deficiency.
Horm Res. 2001;55 Suppl 1:17-20. doi: 10.1159/000063457.
3
Effects of insulin-like growth factor I (IGF-I) therapy on body composition and insulin resistance in IGF-I gene deletion.胰岛素样生长因子I（IGF-I）基因缺失时IGF-I治疗对身体成分和胰岛素抵抗的影响。
J Clin Endocrinol Metab. 2000 Apr;85(4):1407-11. doi: 10.1210/jcem.85.4.6495.
4
胰岛素样生长因子 1 和 2（IGF1、IGF2）在人小胶质细胞中的表达：炎症介质的差异调节。
J Neuroinflammation. 2013 Mar 12;10:37. doi: 10.1186/1742-2094-10-37.
4
Bioinformatic analysis of benzo-α-pyrene-induced damage to the human placental insulin-like growth factor-1 gene.苯并-α-芘诱导人胎盘胰岛素样生长因子-1 基因损伤的生物信息学分析。
Reprod Sci. 2013 Aug;20(8):917-28. doi: 10.1177/1933719112468946. Epub 2013 Jan 23.
5
Role of insulin-like growth factor-1 in the regulation of skeletal growth.胰岛素样生长因子-1 在骨骼生长调节中的作用。
Curr Osteoporos Rep. 2012 Jun;10(2):178-86. doi: 10.1007/s11914-012-0100-9.
6
The many faces of insulin-like peptide signalling in the brain.脑内胰岛素样肽信号的多面性。
Nat Rev Neurosci. 2012 Mar 20;13(4):225-39. doi: 10.1038/nrn3209.
7
Insulin like growth factor-I: a critical mediator of the skeletal response to parathyroid hormone.胰岛素样生长因子-I：甲状旁腺激素对骨骼反应的关键介质。
Curr Mol Pharmacol. 2012 Jun;5(2):135-42.
The insulin-like growth factor-I (IGF-I) gene in individuals born small for gestational age (SGA).小于胎龄儿（SGA）个体中的胰岛素样生长因子-I（IGF-I）基因。
Clin Endocrinol (Oxf). 1999 Oct;51(4):423-7. doi: 10.1046/j.1365-2265.1999.00803.x.
5
Insulin-like growth factor I is essential for postnatal growth in response to growth hormone.胰岛素样生长因子I对于出生后响应生长激素的生长至关重要。
Endocrinology. 1999 Nov;140(11):5178-84. doi: 10.1210/endo.140.11.7151.
6
Long-term treatment of growth hormone insensitivity syndrome with IGF-I. Results of the European Multicentre Study. The Working Group on Growth Hormone Insensitivity Syndromes.使用胰岛素样生长因子-I对生长激素不敏感综合征进行长期治疗。欧洲多中心研究结果。生长激素不敏感综合征工作组。
Horm Res. 1999;51(3):128-34. doi: 10.1159/000023345.
7
Liver-derived insulin-like growth factor I (IGF-I) is the principal source of IGF-I in blood but is not required for postnatal body growth in mice.肝脏来源的胰岛素样生长因子I（IGF-I）是血液中IGF-I的主要来源，但对于小鼠出生后的身体生长并非必需。
Proc Natl Acad Sci U S A. 1999 Jun 8;96(12):7088-92. doi: 10.1073/pnas.96.12.7088.
8
Effects of recombinant human insulin-like growth factor I (IGF-I) therapy on the growth hormone-IGF system of a patient with a partial IGF-I gene deletion.重组人胰岛素样生长因子I（IGF-I）治疗对一名部分IGF-I基因缺失患者生长激素-IGF系统的影响。
J Clin Endocrinol Metab. 1999 May;84(5):1611-6. doi: 10.1210/jcem.84.5.5649.
9
Insulin-like growth factor-I affects perinatal lethality and postnatal development in a gene dosage-dependent manner: manipulation using the Cre/loxP system in transgenic mice.胰岛素样生长因子-I以基因剂量依赖的方式影响围产期致死率和出生后发育：利用转基因小鼠中的Cre/loxP系统进行调控。
Mol Endocrinol. 1998 Sep;12(9):1452-62. doi: 10.1210/mend.12.9.0162.
10
Phenotype: genotype relationships in growth hormone insensitivity syndrome.生长激素不敏感综合征中的表型与基因型关系
J Clin Endocrinol Metab. 1997 Nov;82(11):3529-35. doi: 10.1210/jcem.82.11.4389.