Ohmann C, Franke C, Kraemer M, Yang Q
Koordinierungszentrum für Klinische Studien, Medizinische Fakultät und Funktionsbereich Theoretische Chirurgie, Klinik für Allgemeine und Unfallchirurgie, Heinrich-Heine-Universität Düsseldorf.
Chirurg. 2002 Aug;73(8):769-76. doi: 10.1007/s00104-002-0512-7.
The current incidence of appendicitis is about 100 per 100,000 person-years in Europe/America. Whereas the appendectomy rate is still decreasing, the incidence of appendicitis is now nearly stable. During the last 30 years the incidence of perforated appendicitis has not changed (approximately 20 per 100,000 person-years). Established risk factors for acute appendicitis are age (peak: 10-19 years), sex, and ethnic group/race. Classical theories (diet, hygiene) present illuminating models to explain the rise and fall of incidence in the last century; however, from a contemporary perspective the evidence is insufficient. The study of the epidemiology of appendicitis is complicated by the influence of referral, infrastructure, and surgical treatment strategy on the incidence of acute appendicitis. Therefore, there is a strong need for good prospective studies with high-quality data (e.g., studies directed by a central pathology department).
在欧美地区，目前阑尾炎的发病率约为每10万人年100例。虽然阑尾切除术的比率仍在下降，但阑尾炎的发病率现在几乎稳定。在过去30年中，穿孔性阑尾炎的发病率没有变化（约为每10万人年20例）。急性阑尾炎已确定的风险因素包括年龄（高峰：10 - 19岁）、性别和种族/民族。经典理论（饮食、卫生）提供了有启发性的模型来解释上世纪发病率的起伏；然而，从当代角度来看，证据并不充分。阑尾炎流行病学的研究因转诊、基础设施和手术治疗策略对急性阑尾炎发病率的影响而变得复杂。因此，非常需要高质量数据的良好前瞻性研究（例如，由中央病理科主导的研究）。
