Straube W, Klausch B, Hofmann R, Jenssen H L, Günther J, Köhler H
Arch Gynakol. 1975 Oct 30;218(4):313-22. doi: 10.1007/BF00672332.
By means of the macrophage electrophoretic mobility (MEM) test the supposed immunosuppressive activity of the pregnancy-associated alpha2-glycoprotein (pregnancy zone protein) could be demonstrated significantly. Pregnancy sera and sera of nonpregnant women with hormonal contraception containing this pregnancy protein showed an immunosuppresive activity, too. On the contrary, serum of male donors with the blood group AB and human serum albumin had no inhibitory effects. The results suggest that the pregnancy-associated alpha2-glycoprotein rather influences the afferent limb of the immune response and does not interfere with the activity of the mediator (migration inhibiting factor).
通过巨噬细胞电泳迁移率（MEM）试验，可显著证明妊娠相关α2-糖蛋白（妊娠区蛋白）假定的免疫抑制活性。含有这种妊娠蛋白的妊娠血清以及采用激素避孕的未孕女性血清也显示出免疫抑制活性。相反，AB血型男性供者的血清和人血清白蛋白没有抑制作用。结果表明，妊娠相关α2-糖蛋白对免疫反应的传入支有影响，而不干扰介质（迁移抑制因子）的活性。
