Kraus H, Borst R H, Schuhmann R
Arch Gynakol. 1975 Oct 30;218(4):331-9. doi: 10.1007/BF00672335.
Placental blood-flow rates in rabbits were measured by the indirect method of local apparent conductivity. In our experiments, hypertension was produced by injection or infusion of hypertensive drugs. As a result of hypertension we observed a marked decrease in placental blood flow. Vasoconstriction seems to be the pathophysiologic mechanism causing the reduced blood flow rate. Accordingly, the placenta may not be considered as a "priviledged organ" in circulatory regulations. In our experiments, placental ischemia subsequently to ligatures did not produce hypertension so that the production of a placental pressor-substance could not be demonstrated. If we assume a circulus vitiosus hypertension-placental ischemia-hypertension, the hypertension seems to be the primary cause.
采用局部表观电导率间接法测量家兔胎盘血流速率。在我们的实验中，通过注射或输注高血压药物诱发高血压。高血压导致我们观察到胎盘血流显著减少。血管收缩似乎是导致血流速率降低的病理生理机制。因此，在循环调节中，胎盘不能被视为一个“特权器官”。在我们的实验中，结扎后胎盘缺血并未引发高血压，因此无法证明胎盘升压物质的产生。如果我们假设存在高血压 - 胎盘缺血 - 高血压的恶性循环，那么高血压似乎是主要原因。
