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自我服用圣约翰草对抑郁症状管理的影响。

Implications of self-administered St. John's wort for depression symptom management.

作者信息

Boehnlein Beth, Oakley Linda Denise

机构信息

Marinette County Health & Human Service Department, University of Wisconsin-Madison School of Nursing, USA.

出版信息

J Am Acad Nurse Pract. 2002 Oct;14(10):443-8. doi: 10.1111/j.1745-7599.2002.tb00074.x.

DOI:10.1111/j.1745-7599.2002.tb00074.x
PMID:12426801
Abstract

PURPOSE

To provide nurse practitioners (NPs) with a greater understanding of the complex issues surrounding St. John's wort as a self-treatment for depression; to review laws regulating the production and sale of herbal products in the United States (U.S.); and to review clinical and practice implications for the self-administration of St. John's wort and herbal treatments.

DATA SOURCES

Federal regulations pertaining to herbal products, current research literature, and anecdotal and consumer reports.

CONCLUSIONS

Current research findings suggest that St. John's wort may be an effective treatment for mild depression; however, evidence of significant adverse drug interactions with St. John's wort should not be overlooked.

IMPLICATIONS FOR PRACTICE

Clinical assessment of the mildly depressed patient wishing to self-administer St. John's wort requires basic knowledge of this herbal supplement including regulation and risk information. An open NP-patient relationship helps to ensure patient disclosure of self-administered St. John's wort.

摘要

目的

让执业护士更深入了解圣约翰草作为抑郁症自我治疗方法所涉及的复杂问题;回顾美国有关草药产品生产和销售的法律;并探讨圣约翰草及草药治疗自我给药的临床及实践意义。

数据来源

与草药产品相关的联邦法规、当前研究文献以及传闻和消费者报告。

结论

目前的研究结果表明,圣约翰草可能是治疗轻度抑郁症的有效方法;然而,圣约翰草显著的药物不良反应证据不容忽视。

对实践的启示

对希望自行服用圣约翰草的轻度抑郁症患者进行临床评估,需要掌握这种草药补充剂的基本知识,包括监管和风险信息。开放的护患关系有助于确保患者透露自行服用圣约翰草的情况。

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St John's wort and depression: slight efficacy at best, many drug interactions.圣约翰草与抑郁症:充其量只有轻微疗效,且存在多种药物相互作用。
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St John's wort for depression: a systematic review.圣约翰草治疗抑郁症:一项系统评价。
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