McFarlane Philip A, Pierratos Andreas, Redelmeier Donald A
Home Dialysis, St. Michael's Hospital, Toronto, Ontario, Canada.
Kidney Int. 2002 Dec;62(6):2216-22. doi: 10.1046/j.1523-1755.2002.00678.x.
Home nocturnal hemodialysis (HNHD) can improve clinical and biochemical factors in people with renal failure, but its cost-effectiveness relative to conventional in-center hemodialysis (IHD) is uncertain. We hypothesized that HNHD would provide more dialysis treatments at a lower total cost than IHD.
A prospective one-year descriptive costing study was performed at two centers in Toronto, Canada, involving patients enrolled from a HNHD program (N = 33), and a matched cohort from an IHD program (N = 23). All costs are expressed as mean weekly amount in Canadian year 2000 dollars. A projected mean annual cost (PMA) was calculated also.
The mean number of treatments per week was much higher with HNHD (5.7 vs. 3.0, P = 0.004). Cost categories found to be less expensive for HNHD were staffing (weekly $210 vs. $423, P < 0.001, PMA $10,932 vs. $22,056) and overhead and support (weekly $80 vs. $238, P < 0.001, PMA $4179 vs. $12,393). There was a trend toward lower costs for hospital admissions and procedures (weekly $23 vs. $134, P = 0.355, PMA $1173 vs. $6997) and for medications ($172 vs. $231, P = 0.082, PMA $8989 vs. $12,029). Costs found to be more expensive for HNHD were the cost of direct hemodialysis materials (weekly $318 vs. $126, P < 0.001, PMA $16,587 vs. $6575) and capital costs (weekly $118 vs. $17, P < 0.001, PMA $6139 vs. $871), with a trend toward higher cost for laboratory tests (weekly $33 vs. $26, P = 0.094, PMA $1744 vs. $1364). Physician costs were the same at $128 per week (PMA $6650). The weekly mean total cost for health care delivery was 20% less for HNHD ($1082 vs. $1322, P = 0.006), with projected mean annual costs more than $10,000 lower ($56,394 vs. $68,935).
HNHD provides about three times as many treatment hours at nearly a one-fifth lower cost, with savings evident even when only program and funding-specific costs are considered.
家庭夜间血液透析(HNHD)可改善肾衰竭患者的临床和生化指标,但其相对于传统的中心血液透析(IHD)的成本效益尚不确定。我们推测,与IHD相比,HNHD能以更低的总成本提供更多的透析治疗。
在加拿大多伦多的两个中心进行了一项为期一年的前瞻性描述性成本研究,纳入了来自一个HNHD项目的患者(N = 33),以及来自一个IHD项目的匹配队列(N = 23)。所有成本均以2000年加拿大元的每周平均金额表示。还计算了预计年均成本(PMA)。
HNHD每周的平均治疗次数要高得多(5.7次对3.0次,P = 0.004)。发现HNHD成本较低的类别包括人员配备(每周210加元对423加元,P < 0.001,PMA为10,932加元对22,056加元)以及间接费用和支持(每周80加元对238加元,P < 0.001,PMA为4179加元对12,393加元)。住院和诊疗程序的成本有降低趋势(每周23加元对134加元,P = 0.355,PMA为1173加元对6997加元)以及药物成本(172加元对231加元,P = 0.082,PMA为8989加元对12,029加元)。发现HNHD成本较高的是直接血液透析材料成本(每周318加元对126加元,P < 0.001,PMA为16,587加元对6575加元)和资本成本(每周118加元对17加元,P < 0.001,PMA为6139加元对871加元),实验室检查成本有升高趋势(每周33加元对26加元,P = 0.094,PMA为1744加元对1364加元)。医生成本相同,每周128加元(PMA为6650加元)。HNHD的每周医疗保健提供的平均总成本低20%(1082加元对1322加元,P = 0.006),预计年均成本低超过10,000加元(56,394加元对68,935加元)。
HNHD提供的治疗时间约为IHD的三倍,成本低近五分之一,即使仅考虑项目和特定资金成本,节省也很明显。