Vaidyanathan Subramanian, Soni Bakul M, Oo Tun, Sett Pradipkumar, Hughes Peter L, Singh Gurpreet
Regional Spinal Injuries Centre, District General Hospital, Southport PR8 6PN, United Kingdom.
BMC Urol. 2002 Nov 11;2:12. doi: 10.1186/1471-2490-2-12.
Memokath urethral sphincter stents are used to facilitate bladder emptying in patients with spinal cord injury, but long term follow-up has not been reported.
Case series of ten men with spinal cord injury who underwent insertion of Memokath stents and were followed for up to nine years.
Within four years, the stent had to be removed in nine out of ten patients because of: extensive mucosal proliferation causing obstruction to the lumen of the stent; stone around the proximal end of the stent, incomplete bladder emptying, and recurrent urinary infections; migration of the stent into the bladder related to digital evacuation of bowels; large residual urine; concretions within the stent causing obstruction to flow of urine, and partial blockage of the stent causing frequent episodes of autonomic dysreflexia. In one patient the stent continued to function satisfactorily after nine years.
The Memokath stent has a role as a temporary measure for treatment of detrusor-sphincter dyssynergia in selected SCI patients who do not get recurrent urinary infection and do not require manual evacuation of bowels.
Memokath尿道括约肌支架用于帮助脊髓损伤患者排空膀胱，但长期随访结果尚未见报道。
对10例接受Memokath支架植入术的脊髓损伤男性患者进行病例系列研究，并随访长达9年。
4年内，10例患者中有9例因以下原因不得不取出支架：广泛的黏膜增生导致支架管腔阻塞；支架近端周围结石、膀胱排空不全及反复泌尿系统感染；因手指排便导致支架移入膀胱；大量残余尿；支架内结石导致尿流阻塞，以及支架部分堵塞导致频繁发作自主神经反射异常。1例患者9年后支架仍功能良好。
对于未发生反复泌尿系统感染且无需手动排便的特定脊髓损伤患者，Memokath支架可作为治疗逼尿肌-括约肌协同失调的临时措施。
